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An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
Introducing the Thermo Scientific™ CellInsight™ CX7 LZR High Content Analysis System: the only imaging and analysis platform for advanced performance in screening and analysis.
Bioactivity profiling has been traditionally used to assess the selectivity of new drug candidates in the context of target-based approaches, where pharmacological selectivity is a key requirement.
How to perform successful long term live cell imaging in a high-content analysis system.
Addition of high-throughput technologies and expanded pharmacokinetic services enhances existing support for small molecule drug discovery.
This whitepaper outlines how advances in real-time live-cell monitoring and analysis methods are addressing these changing needs.
This article compares and contrasts a commonly used cell viability assay in manual and automated fashion and provides exemplar data from each scenario.
High-throughput screening (HTS) has become an integral part of early stage drug discovery. This article looks at the use of the latest in vitro 3D cell and tissue culture model systems in HTS. We also highlight some of the bottlenecks and attempt a look into our crystal ball to identify…
27 April 2018 | By TECAN
ABOUT THIS WEBINAR: In this two-part webinar, both automation of P450 (CYP) assays and the automatisation of cellular differentiation processes and compound testing using human induced pluripotent stem cells based assays was covered. Metabolism of drugs is a key factor in compound toxicity, and automated assays which monitor inhibition or…
27 April 2018 | By Eurofins Pharma Discovery Services
In this webinar, we discussed a recent case study where a phenotypic screen was performed using poly I:C / IL-4 stimulated human bronchial epithelial cells. This resulted in the identification of 7 representative hits which provided starting points for new drug discovery opportunities.
26 April 2018 | By Charles River Laboratories
This webinar highlights cell based assays for Parkinson’s disease that include endpoints such as a-synuclein aggregation and mitophagy readouts.
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...
As the drug discovery industry takes on the complex disease states that plague our world, the need for more relevant and timely answers from cell-based assays has become a major challenge.
Next generation sequencing (NGS) has transformed biological research, invigorating the field of genomics, and has increased understanding of our genetic basis.
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
Physiologically relevant screening models have become increasingly important in assay development and the screening of drug candidates.
