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CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation
CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...
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Antiretroviral therapies
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gp120 protein shows promise in HIV vaccine design
Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...
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dCA accelerates HIV-1 suppression in chronically infected cells
Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...
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A3G protein fights HIV as monomer and dimer
A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...
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Bryostatin-1 shows early promise for dormant HIV infection
Scientists have designed a synthetic molecule bryostatin-1 that can reactivate dormant HIV...
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Three-in-one antibody may protect from HIV-like virus
A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...
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HIV vaccine hurdle cleared
An international team of researchers have demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV..
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Researchers identify a new way to treat HIV
Researchers have identified a novel variant "Delta 20" that suppresses the most damaging HIV strains...
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Novel imaging approach offers insights into HIV’s lifecycle
Scientists have used a novel live-cell fluorescent imaging system that has allowed them to identify individual particles associated with HIV...
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Potential broad-spectrum antiviral discovery for herpes virus
Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...
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VRC01 antibody may prolong time to HIV viral rebound
A study has shown the infusion of a broadly neutralising antibody (VRC01) in virally suppressed volunteers associated with a modestly delayed rebound of HIV...
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Scientists discover how membrane necks get constricted and cut
Scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have succeeded in revealing a key mechanism of membrane deformation.
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New biologic drug benefits patients with multi-drug resistant HIV
31 October 2016 | By Niamh Louise Marriott, Digital Content Producer
A new biologic medication - the first for HIV - is showing promise in treating patients with multidrug resistance, according to phase 3 research...
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How NIH’s $30 million research fund will help find HIV cure
20 July 2016 | By Niamh Louise Marriott, Digital Content Producer
The NIH recently awarded $30 million to advance science towards a cure for HIV. Drug Target Review caught up with the Wistar Institute‘s Dr. Luis Montaner, co-leader of the BEAT-HIV project...
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NIH funds six research collaborations to find a cure for HIV
14 July 2016 | By Victoria White, Digital Content Producer
The US National Institutes of Health has awarded $30 million in annual funding to help advance science towards a cure for HIV...
