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Single-nucleus transcriptomics reveals novel epilepsy targets
Study reveals which neurons are most affected by epilepsy, presenting novel targets for seizure drug discovery and development.
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Analytical techniques
webinar
SARS-CoV-2 testing: automation of high-throughput qPCR and COVID-seq
8 October 2020 | By SPT Labtech
In this on-demand webinar, we explored the various methods of COVID-19 testing: qPCR, COVID-seq, antigen and antibody detection, and others. Coupling these assays with low volume, high speed automation has made great strides toward achieving the high-throughput testing essential to ending this pandemic.
news
Epigenetic marks could be the target of future Alzheimer’s therapies
New findings suggest that late-onset Alzheimer's Disease (AD) is driven by epigenetic changes in the brain.
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ebook: From ELISA to epigenetics with HTRF
Overcome HTRF detection challenges with optimised microplate reader settings and simplified analysis.
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ebook: The Axon Guide
Electrophysiology and Biophysics Laboratory Techniques Guide from Molecular Devices.
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Application note: 3D image analysis and characterisation of angiogenesis in organ-on-a-chip model
Many anti-angiogenic drugs have been developed to use in cancer therapy, while pro-angiogenic molecules may hold potential in regenerative applications.
article
How do general anaesthetics cause loss of consciousness?
Inhaled general anaesthetics have been used for over 100 years and continue to be used daily for surgeries around the world. But how do they induce changes to consciousness? This article explores the research that suggests the anaesthetics chloroform and isoflurane disrupt the organisation of lipid rafts within cellular membranes…
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ebook: Cellular Imaging Insights
Learn how to gain insights and expedite studies for 2D and 3D cellular structures with affordable automated cellular imaging.
news
Psychedelic drug discovery enabling discovery of new psychiatric drugs
Having resolved the structure of psychedelic drugs bound to the 5-HT2A serotonin receptor researchers are now developing new therapeutic drugs.
news
Novel pseudo-virion probes to study SARS-CoV-2 viral entry
The non-infectious quantum dot probes are designed to enable researchers to safely study interactions between the SARS-CoV-2 Spike (S) protein and human cells.
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Article: Imaging dataset for COVID-19 research
Molecular Devices helps Recursion produce the largest publicly available set of human cellular morphological data for COVID-19 therapeutic research.
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Interactive demo: Test drive the ImageXpress Pico Automated Cell Imaging System
A powerful, yet affordable, high-content imaging system in your own lab.
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ebook: Get a front row view of your cells
Discover how you can simplify your workflow by combining microplate reading and imaging in a small footprint.
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Cocaine and the brain: identifying targets for addiction therapies
There are currently no licenced pharmaceuticals to treat cocaine addiction. To overcome this issue, US researchers at the University of Alabama at Birmingham have been exploring how cocaine alters transcription in the nucleus accumbens, a region of the brain implicated in compulsive drug use. Here, Hannah Balfour discusses with Dr…
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NGS: offering a glimmer of hope in the fight against COVID-19
Next-generation sequencing (NGS) has become the method of choice for many researchers responding to infectious disease outbreaks and in the present coronavirus pandemic. Here, Pushpanathan Muthuirulan discusses the potential of NGS for rapid diagnosis and explores some of the emerging high-throughput approaches using NGS as a readout for the detection…
