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Analytical techniques

news

Novel method enables mapping of signalling within living cells

22 May 2020 | By Hannah Balfour (Drug Target Review)

A novel microscopy method has enabled researchers to study the flow of signalling information within living cells and could enhance our understanding of cancer metastasis.

news

Chromatography and bioassays used to detect bioactive compounds in plants

11 May 2020 | By Victoria Rees (Drug Target Review)

Bioassays and thin-layer chromatography has been used by scientists to analyse molecules in plant extracts as a fast and cost-effective method for identifying new drug compounds.

fluorescent microscopy of human fibroblasts with nuclei in blue, cytoplasm in green and cell membrane structures in red

news

Self-aligning smart microscope achieves unprecedented resolution

23 April 2020 | By Hannah Balfour (Drug Target Review)

The developers of the ultra-precise single-molecule microscope demonstrated it can resolve interactions between molecules within living cells and is compatible with existing microscopes.

scientists in personal protective equipment looking at samples labelled COVID-19 under a microscope

news

Fundamental molecular research underpins our ability to combat COVD-19, says article

23 April 2020 | By Hannah Balfour (Drug Target Review)

Ali Shilatifard’s article explains how investment in institutes performing molecular research is essential, as it is the foundation for all attempts to combat COVID-19 and other future pandemics.

dendritic cell presenting antigens to T cells with cut away of the T cell receptor and antigen on MHC binding

news

High-throughput protocol for producing tetramer assay probes used to investigate COVID-19

21 April 2020 | By Hannah Balfour (Drug Target Review)

The developers of a novel method to create immunological assay probes for screening T cells has leveraged their new protocol against COVID-19.

news

Chemical tool developed to examine lipids in living cells

20 April 2020 | By Victoria Rees (Drug Target Review)

A new method has been developed by researchers using chemical tools activated by light to influence lipid concentration in living cells.

RNA strand in light blue surrounded by coronavirus particles in darker blue

news

Novel visualisation platform to aid understanding of COVID-19 strain evolution

20 April 2020 | By Hannah Balfour (Drug Target Review)

The visualisation platform is being used to analyse how the SARS-CoV-2 virus causing COVID-19 is evolving and could be used to inform drug design.

tablets, capsules and a laboratory scientist in a white coat on a swirling blue background

news

Screening 10,000 compounds identifies six potential COVID-19 therapeutics

17 April 2020 | By Hannah Balfour (Drug Target Review)

High-throughput screening of thousands of compounds has revealed several candidates, including lead compound ebselen, with the potential for treating COVID-19.

news

Novel 3D imaging technology could improve fluorescence microscopy

15 April 2020 | By Victoria Rees (Drug Target Review)

A new technique called Coded Light-sheet Array Microscopy (CLAM) has been developed by researchers to improve 3D imaging of living specimens.

Cartoon of people of various races/religions/ethnicities all wearing white surgical masks to protect against COVID-19

news

Researchers release 21 openly available SARS-CoV-2 genome sequences

14 April 2020 | By Hannah Balfour (Drug Target Review)

Austrian researchers reveal the first 21 SARS-CoV-2 viral genomes as part of their project to aid in international understanding of how the virus causing COVID-19 mutates.

news

Label-free array system market to be worth $1,600 million by 2025, study finds

14 April 2020 | By Victoria Rees (Drug Target Review)

The global label-free array system market will grow at a compound annual growth rate of 7.44 percent in the forecast period, says new research.

sagittal (side through view) magnetic resonance image of the brain with skull and supporting structures in purple and brain and brainstem in red and orange

article

Refreshing how we approach neuroscience with a novel screening technology

9 April 2020 | By Hannah Balfour (Drug Target Review)

Drug Target Review discusses how NETSseq, a novel profiling technology, is bringing new insights to neurodegenerative and psychiatric diseases.

news

New imaging technique developed to study fungi

9 April 2020 | By Victoria Rees (Drug Target Review)

German researchers have developed a novel imaging technique called expansion microscopy (ExM) to investigate fungi samples.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

news

Organoids for the development of drugs and diagnostics for NASH

3 April 2020 | By Hannah Balfour (Drug Target Review)

Organoids at different stages of non-alcoholic steatohepatitis (NASH) progression have been created to help in drug design and identification of diagnostic biomarkers.

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Analytical techniques