List view / Grid view

Analysis

tablets, syringes and drug vials surrounding the words 'autoimmune disease'

news

Exploration of autoimmune disease target tissues reveals novel drug targets

7 January 2021 | By Hannah Balfour (Drug Target Review)

Researchers suggest that identifying new treatments for autoimmune diseases requires studying the immune system AND target tissues together.

SARS-CoV-2 viral particle in crosshares with words 'target locked' above

news

Analysis finds COVID-19 infection may provide protective immunity

7 January 2021 | By Hannah Balfour (Drug Target Review)

A new analysis suggests SARS-CoV-2-specific antibodies remain relatively stable for eight months and Spike protein-specific memory B cells increase in number over time.

pictur of a red brain within the human anatomy with a glowing red mass indicating a brain tumour

news

Brain injury may drive the development of cancer

5 January 2021 | By Hannah Balfour (Drug Target Review)

A new study reveals that the healing process following a brain injury could initiate the growth of glioblastoma cancers.

Graphic of a person breathing in a stream of SARS-CoV-2 viral particles, some going down the throat to the lungs, others going up to the brain - idea of neurological symptoms of COVID-19

news

Blood vessel damage likely causes neurological symptoms of COVID-19, finds study

4 January 2021 | By Hannah Balfour (Drug Target Review)

A new study suggests that inflammation and blood vessel damage may be the primary causes of neurological symptoms in COVID-19 patients, instead of the virus infecting the brain.

SARS-CoV-2 particles in grey and red - SARS-CoV-2 is the virus that causes COVID-19

news

Single interaction could explain the disparity in COVID-19 effects

17 December 2020 | By Hannah Balfour (Drug Target Review)

According to researchers, an interaction between host microRNA and SARS-CoV-2 could be responsible for the range of disease severities.

SARS-CoV-2 viral particle (which causes COVID-19) circulating in the blood

news

Biomarkers for predicting COVID-19 disease severity

15 December 2020 | By Hannah Balfour (Drug Target Review)

Scientists have created a prognostic classification model which uses biomarkers to help predict an individual’s risk of developing severe COVID-19 symptoms.

red coronavirus particles next to blue DNA strands

news

Genome-wide association study reveals targets for COVID-19 treatments

14 December 2020 | By Hannah Balfour (Drug Target Review)

The study found five key genetic differences when they compared sequences from severe COVID-19 patients to healthy individuals.

SARS-CoV-2 particle in grey surrounded by various blue and green antibodies all on a red background

news

Triggering an IgA response could increase COVID-19 vaccine efficacy

8 December 2020 | By Hannah Balfour (Drug Target Review)

Two new studies suggest that SARS-CoV-2-specific IgA antibodies are more neutralising and therefore COVID-19 vaccines should encourage an IgA response.

Outline of a brain in purple with dark brown coronavirus particles within it

news

Researchers discover how SARS-CoV-2 reaches the brain

1 December 2020 | By Hannah Balfour (Drug Target Review)

A new study has identified the mechanisms through which the SARS-CoV-2 virus enters the brain and how the immune system responds once it does.

news

Transcription factor source for customised stem cell programming

1 December 2020 | By Hannah Balfour (Drug Target Review)

Researchers have found a way to systematically extract various cell types from induced pluripotent stem cells and made their transcription factor source accessible for other scientists.

coronavirus particles surrounded by red blood cells

news

CD209 antigen could be a promising target for preventing severe COVID-19

26 November 2020 | By Hannah Balfour (Drug Target Review)

Researchers reveal how two genetic variations may contribute to COVID-19 disease severity and suggest the product of one, the CD209 antigen, may be a potential drug target.

news

Endosomal trafficking could be a target for Alzheimer’s therapies

26 November 2020 | By Hannah Balfour (Drug Target Review)

Researchers have shown that 70 percent of Alzheimer’s patients have high levels of proteins associated with dysfunction in the endosomal trafficking system in their spinal fluid.

news

Proteogenomic analysis offers insights into paediatric brain tumours

26 November 2020 | By Victoria Rees (Drug Target Review)

The first comprehensive survey of genomics, transcriptomics, global proteomics and phosphoproteomics has revealed insights into paediatric brain tumours.

news

Network modelling reveals a potential new Alzheimer’s therapy

25 November 2020 | By Hannah Balfour (Drug Target Review)

Researchers used integrative network biology analysis to identify the molecular mechanisms that may drive Alzheimer’s and identified a potential therapeutic intervention.

cartoon of the cross-section of a purple ion channel in a blue lipid bylayer (plasma mebrane)

news

New insight to guide discovery of drugs targeting ion channels

24 November 2020 | By Hannah Balfour (Drug Target Review)

The study shows how drug-like small molecules inhibit the activity of Transient Receptor Potential Canonical 1/4/5 (TRPC1/4/5) channels and could transform the development of future therapies.

Cookie	Type	Duration	Description
cookielawinfo-checkbox-advertising-targeting	persistent	1 year	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".
cookielawinfo-checkbox-analytics	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Analytics".
cookielawinfo-checkbox-necessary	persistent	1 year	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-performance	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Performance".
PHPSESSID	session	1 year	This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
viewed_cookie_policy	persistent	1 year	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
zmember_logged	session	1 year	This session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users.

Cookie	Type	Duration	Description
advanced_ads_browser_width	persistent	1 month	This cookie is set by Advanced Ads and measures the browser width.
advanced_ads_page_impressions	persistent	2 years	This cookie is set by Advanced Ads and measures the number of previous page impressions.
advanced_ads_pro_server_info	persistent	1 month	This cookie is set by Advanced Ads and sets geo-location, user role and user capabilities. It is used by cache busting in Advanced Ads Pro when the appropriate visitor conditions are used.
advanced_ads_pro_visitor_referrer	persistent	1 year	This cookie is set by Advanced Ads and sets the referrer URL.
bscookie	persistent	2 years	This cookie is a browser ID cookie set by LinkedIn share Buttons and ad tags.
IDE	persistent	2 years	This cookie is set by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
li_sugr	persistent	3 months	This cookie is set by LinkedIn and is used for tracking.
UserMatchHistory	persistent	1 month	This cookie is set by Linkedin and is used to track visitors on multiple websites, in order to present relevant advertisement based on the visitor's preferences.
VISITOR_INFO1_LIVE	persistent	5 months	This cookie is set by YouTube. Used to track the information of the embedded YouTube videos on a website.

Cookie	Type	Duration	Description
bcookie	persistent	2 years	This cookie is set by LinkedIn. The purpose of the cookie is to enable LinkedIn functionalities on the page.
GPS	persistent	30 minutes	This cookie is set by YouTube and registers a unique ID for tracking users based on their geographical location
lang	session	1 year	This cookie is set by LinkedIn and is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website.
lidc	persistent	1 day	This cookie is set by LinkedIn and used for routing.
lissc	persistent	11 months	This cookie is set by LinkedIn share Buttons and ad tags.
vuid	persistent	2 years	We embed videos from our official Vimeo channel. When you press play, Vimeo will drop third party cookies to enable the video to play and to see how long a viewer has watched the video. This cookie does not track individuals.
wow.anonymousId	persistent	2 years	This cookie is set by Spotler and tracks an anonymous visitor ID.
wow.schedule	persistent	20 minutes	This cookie is set by Spotler and enables it to track the Load Balance Session Queue.
wow.session	persistent	20 minutes	This cookie is set by Spotler to track the Internet Information Services (IIS) session state.
wow.utmvalues	persistent	20 minutes	This cookie is set by Spotler and stores the UTM values for the session. UTM values are specific text strings that are appended to URLs that allow Communigator to track the URLs and the UTM values when they get clicked on.
_ga	persistent	2 years	This cookie is set by Google Analytics and is used to calculate visitor, session, campaign data and keep track of site usage for the site's analytics report. It stores information anonymously and assign a randomly generated number to identify unique visitors.
_gat	persistent	1 minute	This cookies is set by Google Universal Analytics to throttle the request rate to limit the collection of data on high traffic sites.
_gid	persistent	1 day	This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. The data collected including the number visitors, the source where they have come from, and the pages visited in an anonymous form.

Cookie	Type	Duration	Description
cf_ob_info	persistent	1 minute	This cookie is set by Cloudflare content delivery network and, in conjunction with the cookie 'cf_use_ob', is used to determine whether it should continue serving “Always Online” until the cookie expires.
cf_use_ob	persistent	1 minute	This cookie is set by Cloudflare content delivery network and is used to determine whether it should continue serving “Always Online” until the cookie expires.
free_subscription_only	session	1 year	This session cookie is served by our membership/subscription system and controls which types of content you are able to access.
ls_smartpush	persistent	1 month	This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site.
one_signal_sdk_db	persistent	Until cleared	This cookie is set by OneSignal push notifications and is used for storing user preferences in connection with their notification permission status.
YSC	session	1 year	This cookie is set by Youtube and is used to track the views of embedded videos.

Recommended

Analysis