news SARS-CoV-2 immunodominant epitopes identified as vaccine candidates 12 June 2020 | By Victoria Rees (Drug Target Review) Researchers have analysed the SARS-CoV-2 proteome to reveal seven promising immunodominant epitopes that could aid in the development of a COVID-19 vaccine.
news Computational approach identifies novel COVID-19 vaccine targets 9 June 2020 | By Hannah Balfour (Drug Target Review) Researchers used computational tools to identify regions of the SARS-CoV-2 virus that could potentially provide a safe and long-term immune response.
article Using scientific literature to aid the development of a safe and effective COVID-19 vaccine 2 June 2020 | By Victoria Rees (Drug Target Review) Researchers in the US describe how they utilised previously published scientific literature to guide the design of their potential COVID-19 vaccine.
news White blood cells as a novel early indicator of vaccine efficacy 21 May 2020 | By Hannah Balfour (Drug Target Review) Researchers demonstrate that a subpopulation of circulating white blood cells can act as an early indicator of vaccine efficacy, with potential implications for COVID-19 drug development.
news Protective immunity to SARS-CoV-2 shown in non-human primates 21 May 2020 | By Hannah Balfour (Drug Target Review) Macaques were protected against SARS-CoV-2 infection both after an initial infection and vaccination with a prototype vaccine, researchers suggest humans could respond similarly.
news Analysis of immune response to SARS-CoV-2 gives hope for COVID-19 vaccines 19 May 2020 | By Victoria Rees (Drug Target Review) A detailed analysis of the body's immune response to COVID-19 has revealed that it can recognise SARS-CoV-2 in many ways, meaning vaccines can be used to stop the spread of the virus.
news Oxford University and NIH COVID-19 vaccine shows success in rhesus macaques 18 May 2020 | By Victoria Rees (Drug Target Review) A vaccine currently in Phase I clinical trials was effective at inducing immune responses against SARS-CoV-2 in mice and rhesus macaques.
article Utilising an interleukin-12 plasmid: a novel COVID-19 vaccine 13 May 2020 | By Victoria Rees (Drug Target Review) Dr Bernard Fox from Providence Cancer Institute explains how OncoSec’s CORVax12 vaccine works to potentially combat COVID-19.
news Procedure developed to create murine models of COVID-19 for testing of therapeutics and vaccines 12 May 2020 | By Victoria Rees (Drug Target Review) Russian researchers have created a process for the development of mouse models for use in pre-clinical studies of COVID-19 treatments and vaccines.
news Researchers develop promising MERS vaccine, with potential for COVID-19 11 May 2020 | By Victoria Rees (Drug Target Review) A MERS vaccine, which uses RNA-based adjuvants, has demonstrated efficacy in non-human primates and is now being developed as a prophylactic for COVID-19.
news Fundamental molecular research underpins our ability to combat COVD-19, says article 23 April 2020 | By Hannah Balfour (Drug Target Review) Ali Shilatifard’s article explains how investment in institutes performing molecular research is essential, as it is the foundation for all attempts to combat COVID-19 and other future pandemics.
news UK government funds 21 new research projects into COVID-19 20 April 2020 | By Victoria Rees (Drug Target Review) A total of 21 COVID-19 research projects have been granted funding by the UK government, including vaccine and therapeutic development.
news Plant bio-factories contributing to the COVID-19 fight 15 April 2020 | By Hannah Balfour (Drug Target Review) Researchers have made the genome of the Nicotiana benthamiana plant, a commonly used bio-factory organism, public to aid in COVID-19 vaccine production.
article COVID-19 and big pharma: what are 15 leading companies doing to develop a coronavirus vaccine? 9 April 2020 | By Victoria Rees (Drug Target Review) A new report has revealed the vaccine R&D efforts of 15 of the leading pharmaceutical companies to combat the COVID-19 coronavirus.
news MERS vaccine candidate could hold promise for COVID-19 vaccine 8 April 2020 | By Hannah Balfour (Drug Target Review) The vaccine candidate protected all murine models from a lethal MERS infection and could also be effective against the SARS-CoV-2 virus causing COVID-19.
