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Dr Matthew Disney

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Scientists target ALS and dementia RNA using novel molecule

The small molecule successfully targeted the C9orf72 gene that causes…

28 October 2021 | By Anna Begley (Drug Target Review)

The small molecule successfully targeted the C9orf72 gene that causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

news

Researchers develop drug discovery tool for RNA

Scientists have created a drug discovery platform that enables the…

16 December 2020 | By Victoria Rees (Drug Target Review)

Scientists have created a drug discovery platform that enables the discovery and optimisation of RNA-targeting compounds.

SARS-CoV-2 viral particle next to a single RNA strand

news

Novel RNA-targeting molecule can halt SARS-CoV-2 replication

The C5 compound targets the frameshifting element that allows SARS-CoV-2…

1 October 2020 | By Hannah Balfour (Drug Target Review)

The C5 compound targets the frameshifting element that allows SARS-CoV-2 to effectively replicate and marks the genome for destruction to stop the infection spreading.

news

Study shows heart repair factor boosted by RNA-targeting compound

Researchers have discovered compounds able to restart production of VEGF-A…

25 August 2020 | By Victoria Rees (Drug Target Review)

Researchers have discovered compounds able to restart production of VEGF-A in cellular models, which rebuilds blood vessels and muscle in damaged heart tissue.

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Recommended

Dr Matthew Disney

Scientists target ALS and dementia RNA using novel molecule

Researchers develop drug discovery tool for RNA

Novel RNA-targeting molecule can halt SARS-CoV-2 replication

Study shows heart repair factor boosted by RNA-targeting compound