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Inhibiting PIP4K enzymes could help immune system fight cancer
Researchers identified a potential therapeutic involving the inhibition of PIP4K enzymes which could enable the immune system to destroy tumour cells.
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Southampton University
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Spikes from AstraZeneca COVID-19 vaccine resemble SARS-CoV-2 S proteins
Using cryo-electron microscopy, researchers have shown that the Spike (S) protein on cells exposed to the AstraZeneca vaccine is highly similar to the SARS-CoV-2 S protein.
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Gold nanoparticles designed to seek out and isolate human bone stem cells
A team has designed gold nanoparticles to reveal specific bone stem cells, which could lead to treatments for major bone fractures.
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T-cell exhaustion may limit long-term immunity in COVID-19 patients
Researchers suggest patients who develop mild COVID-19 may not be able to fight reinfection very effectively because their CD8+ T cells show signs of exhaustion.
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Mass spec used to reveal glycan structures of COVID-19 Spike protein
High-resolution mass spectrometry has been used by researchers to map the glycan-processing states of the Spike protein of the SARS-CoV-2 virus, which causes COVID-19.
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Researchers find drug improves cancer immunotherapy in mice
A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.
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Stain-less laser-based imaging used for regenerative medicine research
Researchers create images from stem cells as part of an investigation into new optical techniques to monitor the cells' development...
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Research reveals antibody treatment pathway for severe allergic asthma
Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...
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New molecules could help in the fight to prevent cystic fibrosis
9 June 2016 | By Victoria White, Digital Content Producer
Researchers have identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis...
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A drug that heals broken bones faster and better
23 November 2015 | By Victoria White
Using bone samples from people undergoing hip replacement surgery, researchers were able to show that a drug that activates the Wnt pathway causes stem cells found within bones to divide and to turn into more bone cells...
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Possible solution for Alzheimer’s immunotherapy side effect
6 November 2015 | By Victoria White
Scientists have discovered that small changes in anti-amyloid antibodies preserves the immunotherapeutic activity without the inflammatory side effects...
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Scientists investigate the function of protein MHC1
6 November 2015 | By Victoria White
The scientists have been awarded £700,000 to work in collaboration with Unilever scientists to explore ways to minimise allergic reactions to additives in healthcare products...
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Scientists discover exercise mimicking molecule ‘compound 14’
28 July 2015 | By Victoria White
Scientists have developed a molecule, called 'compound 14', that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity...
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Formation of nano- and micro-scale drug delivery systems using microfluidic technology
The recent developments in microfluidic technology have provided an effective microreactor platform for the production of a range of pharmaceutically related materials in both nano- and micro-scale. This can be attributed to the unique characteristics that microfluidic-based reactors offer in terms of controllability and uniformity of the material characteristics, compared…