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University of Pittsburgh

Doctor measuring arterial blood pressure using stethoscope

news

Algorithm identifies cancer drugs to treat pulmonary hypertension

21 October 2021 | By Anna Begley (Drug Target Review)

Scientists have identified potential cancer drugs to treat pulmonary hypertension using experimental and computational approaches.

news

Deletions in SARS-CoV-2 Spike protein drive antibody escape, study shows

4 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that SARS-CoV-2 evades immune responses by deleting parts of its genetic sequence that encode for the Spike protein.

news

New CRISPR system edits body’s response to prevent immunity against AAVs

4 September 2020 | By Victoria Rees (Drug Target Review)

A novel CRISPR system that suppresses genes related to adeno-associated virus (AAV) antibody production has been developed to prevent immunity against the gene therapy.

man holding head due to headache/stroke, with brain visible

news

ZT-1a compound could be an alternative to surgery for brain swelling

3 March 2020 | By Hannah Balfour (Drug Target Review)

Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.

news

Identifying the right mouse model for Huntington’s disease drug development

12 December 2019 | By Rachael Harper (Drug Target Review)

Scientists have evaluated mouse models used for developing treatments for mood disorders associated with Huntington's disease and have recommended which have greater potential for success.

news

Mechanism identified of impaired dendritic cell function that weakens response to cancer

15 December 2017 | By Dr Zara Kassam (Drug Target Review)

New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...

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Recommended

University of Pittsburgh

Algorithm identifies cancer drugs to treat pulmonary hypertension

Deletions in SARS-CoV-2 Spike protein drive antibody escape, study shows

New CRISPR system edits body’s response to prevent immunity against AAVs

ZT-1a compound could be an alternative to surgery for brain swelling

Identifying the right mouse model for Huntington’s disease drug development

Mechanism identified of impaired dendritic cell function that weakens response to cancer