news Stem cell therapy repairs injured peripheral nerves in animal models 12 October 2021 | By Anna Begley (Drug Target Review) Gingiva-derived mesenchymal stem cells were used to surgically repair injured peripheral nerves, showing potential for new therapies.
news CRISPR screening tool exposes new leukaemia drug target 29 September 2021 | By Anna Begley (Drug Target Review) A CRISPR screening tool identified a new target for acute myeloid leukaemia with fewer side effects than current approaches.
news RN7SL1 RNA shown to activate T cells to fight against cancer 6 September 2021 | By Anna Begley (Drug Target Review) A new study found that the RNA RN7SL1 can activate T cells to seek out cancer cells, potentially improving cellular treatments.
news Existing drug may improve immune response to leukaemia treatment 18 August 2021 | By Anna Begley (Drug Target Review) Researchers identified the inhibitor JQ1 as a potential drug to improve immune response to CAR T-cell therapies in leukaemia patients.
news Promising new avenue to tackle obesity-related diabetes 2 July 2021 | By Mandy Parrett (Drug Target Review) New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
news Novel mRNA vaccine provides full protection against malaria in mice 21 June 2021 | By Victoria Rees (Drug Target Review) A new mRNA vaccine based on the malaria circumsporozoite protein was shown to elicit a robust immune response in mice.
news Stem cell study illuminates cause of dilated cardiomyopathy (DCM) 2 February 2021 | By Victoria Rees (Drug Target Review) A study using stem cells has revealed that DCM-causing mutations in LMNA disrupt the organisation of DNA in the nucleus of heart muscle cells.
news Knee injection shows promise as osteoarthritis treatment in mice 18 January 2021 | By Victoria Rees (Drug Target Review) Scientists have found that a new knee injection using nanomedicine could prevent the effects of osteoarthritis.
article CRISPR: three new developments in the world of gene editing 14 January 2021 | By Victoria Rees (Drug Target Review) In this article, we outline three recent studies that have advanced the potential uses of CRISPR in the biomedical field.
news Enzyme vital for sperm formation potential target for male infertility 27 March 2020 | By Victoria Rees (Drug Target Review) Researchers have identified an enzyme required for the formation of sperm and chromosomal pairing, which they say could be a target to treat male infertility.
news Study paves way for new vaccines to protect infants against infections 9 January 2020 | By Rachael Harper (Drug Target Review) An mRNA vaccine has been developed which has elicited strong immune responses in mice in the presence of maternal antibodies.
news Study shows new strategies for HIV control 23 December 2019 | By Drug Target Review New research goes against the paradigm of HIV control that focuses on killing off infected cells and supports a model in which viral suppression could possibly serve as a cure.
article DTR’s news round-up 2019: the stories that defined the year 18 December 2019 | By Drug Target Review Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.
news HIV infant model opens new avenues for research 9 September 2019 | By Rachael Harper (Drug Target Review) An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.
news Interferon pathway could provide drug target for cancers 8 August 2019 | By Victoria Rees (Drug Target Review) A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
