news Scientists uncover structural biology details of SARS-CoV-2 infection 26 February 2021 | By Victoria Rees (Drug Target Review) Researchers have used computer simulations to model how the SARS-CoV-2 fusion peptide interacts with and penetrates the cell membrane.
news Tracking SARS-CoV-2 evolution: notable mutations and potential targets 26 August 2020 | By Hannah Balfour (Drug Target Review) Researchers report that while the spike protein and RNA polymerase proteins have stabilised, other regions of the SARS-CoV-2 genome are becoming increasingly variable.
article Five of the most recent microscopy developments 23 July 2020 | By Victoria Rees (Drug Target Review) Drug Target Review highlights five of the latest imaging advancements in the field of microscopy.
news Microfluidics device to detect cancer cells in blood 26 February 2019 | By Iqra Farooq (Drug Target Review) A recently developed microfluidics device is able to detect and separate out cancer cells in blood, without the need for dilution...
news Potential drug targets found by muting large silent genes 2 January 2019 | By Iqra Farooq (Drug Target Review) Streptomyces bacteria has been used to identify compounds that could lead to the production of drugs to treat various conditions...
news Dietary fibre could be key to prevent age related decline in brain functions 17 September 2018 | By Iqra Farooq (Drug Target Review) Researchers have identified that dietary fibre could be beneficial for older people, to prevent inflamed microglia leading on to cognitive disorders...
news Viral DNA mechanism discovery could lead to improved infection control 5 September 2018 | By Drug Target Review A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell.
news Scientists develop TSA-Seq technique for precise 3D mapping of human genome 29 August 2018 | By Drug Target Review Despite the human genome being first sequenced almost 20 years ago, researchers know comparatively little about how the genome is organised within cells. But a new TSA-Seq technique is changing that.
news CRISPR technique skips over portions of genes that can cause disease 17 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
news pGENMi predicts genomic features associated with drug responses 13 July 2018 | By Drug Target Review A new system, pGENMi, could predict genomic features associated with drug responses, by identifying differences in gene expression...
news Elastic microspheres expand understanding of embryonic development and cancer cells 15 May 2018 | By Drug Target Review A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells...
news NAMD software brings subatomic resolution to computational microscope 27 March 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have built a computational microscope that can simulate the atomic and subatomic forces that drive molecular interactions...
news Pixelated gene expression tool provides fast accurate results for RNA analysis 22 January 2018 | By Drug Target Review Researchers have demonstrated how a pixelated gene expression tool can accurately measure RNA levels more quickly than existing methods allow.
news Biomarkers as effective at predicting sepsis as patient monitoring 8 September 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified five key sepsis biomarkers and looked at whether they had the same or better predictive power as traditional methods...
news Quick test finds signs of sepsis in a single drop of blood 7 July 2017 | By Niamh Marriott (Drug Target Review) A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood.