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Blocking ApoE4 may prevent nerve cell death in Alzheimer’s disease
Researchers have identified that the presence of ApoE4 exacerbates the brain damage caused by toxic tangles of tau protein...
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California University
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New fluorescent dyes could advance biological imaging
With a new technique swapping out specific chemical building blocks in rhodamines researchers have generated a fluorescent dye for biological imaging...
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Study identifies new brain death pathway in Alzheimer’s disease
Evidence that the activation of a biological pathway necroptosis is closely linked with Alzheimer's...
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Specialised blood vessels enhance tumour-fighting immunotherapy
The successful combination of two therapies results in the growth of specialised vessels that deliver cancer-fighting immune cells to a tumour, potentially leading to more effective treatments and longer survival periods.
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Cell death research shows promise for preventing Alzheimer’s
Alzheimer’s disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. Currently, the predominant theory behind Alzheimer’s disease is the “amyloid hypothesis,” which states that abnormally increased levels of amyloid beta (Aβ) peptides outside of brain cells produce a variety of low molecular weight…
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ESCMID and ASM’s review need for new strategies and tactics to fight antimicrobial resistance
11 October 2016 | By Niamh Louise Marriott, Digital Content Producer
The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the American Society for Microbiology (ASM) have just closed a joint conference in Vienna, which aimed to help researchers accelerate the development of new antimicrobials and to shed light on the challenges associated with antimicrobial resistance.
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Research suggests ion channel blocking drugs could be used in cancer therapy
12 August 2015 | By Author: Katie Sadler, Digital Content Producer, Drug Target Review
Research carried out by University of California San Francisco (UCSF) has revealed ion channel blocking drugs could play a part in cancer therapy. The common class of channel blocking drugs, which are used to treat cardiac, neurological, and psychiatric disorders, could prove to be beneficial in cancer treatment according to…
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New biomarkers might help personalise metastatic colorectal cancer treatment
18 June 2015 | By Victoria White
New research has revealed two genes that could help physicians make more informed treatment decisions for patients with colorectal cancer...
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Michelle Arkin
3 February 2014 | By
Associate Director, Biology, Small Molecule Discovery Center, University of California