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CRISPR: three new developments in the world of gene editing
In this article, we outline three recent studies that have advanced the potential uses of CRISPR in the biomedical field.
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University of California Berkeley
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Nobel Prize in Chemistry awarded to scientists who discovered CRISPR-Cas9
Emmanuelle Charpentier and Jennifer Doudna have been given the 2020 Nobel Prize in Chemistry for their discovery and development of CRISPR-Cas9 genome editing.
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Novel CRISPR enzyme could expand the range of targets for gene therapy
The novel CRISPR-CasΦ enzyme, isolated from bacteriophages, can target a wider range of genetic sequences, say the researchers.
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Technique for 2D printing of cells developed by researchers
A study has demonstrated the success of a 2D printing method to create cell arrays that reflect the body's natural environment, allowing researchers to study stem cell differentiation.
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Molecular ‘switch’ could help treat or reverse age-related diseases
A molecular 'switch' that controls the immune machinery responsible for chronic inflammation has been identified which could help treat or even reverse the development of age-related conditions like Alzheimer's, Parkinson's, cancer and diabetes.
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NLRP3 inflammasome ‘off switch’ reverses effects of chronic inflammation
Research into age-related chronic inflammatory disorders has identified an ‘off switch’ on the NLRP3 inflammasome that could be targeted in new therapies.
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Drug sponge could minimise effects of cancer therapy
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
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CRISPR-Gold used to reduce repetitive behaviours in FXS
Gold nanoparticles carried Cas9 enzyme into brain, editing receptor and lessening burying behaviour...
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LXB4 lipid protect neurons against glaucoma
Researchers have identified a new neuroprotective factor that has the potential to help people suffering from glaucoma...
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Cytokine molecules unearth development of progressive MS
Scientists have uncovered two closely related cytokines molecules involved in cell communication that explain why some people develop progressive MS...
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New fluorescent dyes could advance biological imaging
With a new technique swapping out specific chemical building blocks in rhodamines researchers have generated a fluorescent dye for biological imaging...
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CRISPR gives new insight into autoimmune disorders
Researchers have used a modified version of the gene-editing technique CRISPR in search for gene activators...
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Using single-cell RNA sequencing to track stem cell development
Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.
