news
Mitochondrial enzyme found to block ferroptosis, presenting cancer target
The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) can block cell death, new research has shown, making it a cancer drug target.
List view / Grid view
The University of Texas MD Anderson Cancer Center
news
Study defines small-cell lung cancer subtypes and therapeutic vulnerabilities
Researchers have identified four unique subtypes of small-cell lung cancer (SCLC) following the characterisation of cell types.
news
NIK could be key to enhancing the effects of immunotherapy
Immunology study shows that NF-kappa B-inducing kinase (NIK) is critical to T cell metabolism and the antitumour immune response.
news
HDAC3 inhibitors: a potential treatment for non-Hodgkin lymphomas?
A murine study found histone deacetylase 3 (HDAC3) inhibitors reverse epigenetic changes caused by CREBBP mutations found in lymphomas and could be developed into a novel therapy.
news
Stephen Hahn nominated to be new FDA commissioner
President Trump has announced his intent to nominate Stephen Hahn as Commissioner of Food and Drugs at the Department of Health and Human Services.
news
Promising drug developed for ovarian and pancreatic cancers
An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
news
New potential liver cancer treatment found with biomarker-guided strategy
A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.
news
FGL2 protein may be an effective target for GBM
Researchers have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance...
news
PKCδ enzyme linked to therapy resistance in lung cancer
The enzyme protein kinase C delta (PKCδ) found in NSCLC tumors prevents tyrosine kinase inhibitors (TKIs) from forestalling cancer...
