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Researchers identify COVID-19 proteins that cause blood vessel damage
Scientists revealed five proteins that cause blood vessel damage in COVID-19 patients, potentially leading to new drug targets.
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Tel Aviv University
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AI platform developed to reveal how bacteria infect intestines
A new artificial intelligence (AI) method has been created to uncover which proteins enable bacteria to infect human intestines.
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Team sheds light on the co-ordination of neural stem cell activation
Scientists have visualised the spatial and temporal distribution of neural stem cell activation in zebrafish models.
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Body-on-chip technology: resolving current limitations in drug discovery
Researchers have developed a new body-on-chip technology that can demonstrate the pharmacokinetics and pharmacodynamics of drugs in a pre-clinical setting without the need for animal testing.
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DTR’s news round-up 2019: the stories that defined the year
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.
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PJ34 triggers self-destruction of human pancreatic cancer cells
A study conducted on human pancreatic tumours transplanted in mice reveals promise for an effective therapy in the future, say researchers.
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Proteomic approach reveals metastatic melanoma resistance to therapies
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
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Study finds inhibiting inflammatory pathway could be brain metastasis target
Researchers have revealed a key inflammation mechanism that contributes to melanoma brain metastasis and could be a therapeutic target.
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Novel nano-vaccine for melanoma developed
A novel nano-vaccine has been developed which has proven effective in treating primary tumours and metastases that result from melanoma.
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Screening identifies gene which protects cells from Zika virus
Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
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Ubiquilin-4 biomarker links cancer progression to genome instability
High level of specific protein in tumours indicates prognosis as well as optimal treatments...
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Breast cancer recruits cells from bone marrow to boost growth
A study has shown that breast cancer uses stromal cells originally formed in bone marrow to boost their growth and metastasis of the cancer...
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Drug candidate offers hope of vocal improvement for ADNP syndrome
Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.
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Changes to specific MicroRNA involved in development of Lou Gehrig’s disease
A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS).
