news Compound that targets BRAT1 protein could be used to kill cancer cells 22 April 2021 | By Victoria Rees (Drug Target Review) Having synthesised the curcusone D compound, researchers demonstrated its promise as the first BRAT1 inhibitor, making it a potential cancer therapy.
news New 3D cell culture method could enable personalised cancer therapies 13 November 2020 | By Victoria Rees (Drug Target Review) A team has extracted single tumour cells from existing cell lines to create 3D cell cultures that could allow for personalised cancer therapies.
news Novel compounds show efficacy against C. diff 28 September 2020 | By Hannah Balfour (Drug Target Review) Researchers have developed two novel trifluoromethylthio compounds which showed potent activity in protecting mice from Clostridioides difficile (C. diff) infection.
article Translating novel drug success in animals to humans 12 August 2020 | By Victoria Rees (Drug Target Review) A team has developed a predictive tool called TransComp-R which could be used to reveal whether new drugs that have been effective in animals will have positive outcomes in humans.
news IL-27 could work as potential immunotherapy against cancers 8 April 2020 | By Victoria Rees (Drug Target Review) Researchers have created a new kind of immunotherapy using the interleukin-27 (IL-27) cytokine to effectively combat tumours in vitro and in vivo.
news Drug discovery could be improved with new collapsible basket technology 9 March 2020 | By Rachael Harper (Drug Target Review) A collapsible basket technology has been developed to significantly accelerate the analysis process when scientists are developing new medicines.
news Deep learning network used to model protein complexes 13 January 2020 | By Victoria Rees (Drug Target Review) A new study has developed a deep learning approach that analyses protein interactions, which could improve the design of drugs in the future.
news Platform may find new options for mental health treatment 16 October 2019 | By Rachael Harper (Drug Target Review) A drug discovery platform for mental health treatment could also help to identify mechanisms for the treatment of substance use disorders.
article Five newest developments for imaging in drug research 12 August 2019 | By Victoria Rees (Drug Target Review) Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
news Drug compound could be next-generation treatment for aggressive form of AML 29 January 2019 | By Drug Target Review Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
news New imaging tools that trace key breast cancer enzymes may help guide therapies 7 December 2018 | By Drug Target Review Series of molecules may provide more reliable relief with fewer side effects...
news MRI tool to cure digestive disorders 26 October 2018 | By Drug Target Review Purdue researchers have paved the way for more precise treatment for disorders in the gastrointestinal tract such as gastroparesis...
news Breast tissue simulations address enhanced MRI delays 25 September 2018 | By Iqra Farooq (Drug Target Review) Researchers address the delay of enhanced MRI cancer detection using simulations of women's breast tissue and higher MRI strengths...
news New 3D ‘nanoscope’ facilitates improved brain imaging for Alzheimer’s research 17 July 2018 | By Drug Target Review Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.
news MiR-223 could help treat cancer and asthma 23 February 2018 | By Drug Target Review A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer...
