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Gene therapy bolsters Parkinson’s drug benefits in pre-clinical study
The gene therapy restored the ability of neurons to convert levodopa to dopamine and may help develop therapies to slow disease progression.
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Northwestern University
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Promising new avenue to tackle obesity-related diabetes
New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
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Researchers reveal 3D structure responsible for gene expression
Researchers have produced the first 3D image of the Mediator-bound pre-initiation complex, key in the regulation of gene expression.
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Neuron damage from ALS reversed with new compound
Scientists have developed a compound that stops the degeneration of upper motor neurons, a contributor to amyotrophic lateral sclerosis (ALS).
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New technology enables predictive design of engineered human cells
Researchers have developed a computer modelling programme that can produce genetic circuits for cellular engineering.
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Novel nanoscale 4D printer could be used for drug research
A novel 4D printer has been created which can combine organic chemistry, surface science and nanolithography to design surfaces with organic or biological molecules for drug research.
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Mass spectrometry approach allows researchers to make precise protein measurements
A new method for weighing proteins at the atom level, called individual ion mass spectrometry, has been developed by American researchers.
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New machine learning algorithm uncovers time-delayed interactions in cells
Scientists have designed a new machine learning algorithm that uses time-series data to uncover underlying biological networks.
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A new approach to Organ-on-a-Chip
Draper's Joe Charest explains how synthetic organoids can lead to safer drug testing, and why organ-on-a-chip technology is the future of drug discovery...
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Manipulating HCN channels could lead to new depression treatments
12 July 2016 | By Victoria White, Digital Content Producer
Using gene therapy, scientists from Northwestern Medicine have identified a target in the brain that could lead to new treatments for depression...
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TMEM230 gene shown to cause Parkinson’s disease
6 June 2016 | By Victoria White, Digital Content Producer
Scientists from Northwestern University have discovered a new cause of Parkinson's disease - mutations in a gene called TMEM230...
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Breast cancer drug suppresses dangerous brain seizures
13 May 2016 | By Victoria White, Digital Content Producer
Scientists also found that inhibiting oestrogen synthesis just after seizure onset strongly suppressed seizures in both sexes...
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Biodegradable nanoparticles that halt asthma
18 April 2016 | By Victoria White, Digital Content Producer
A biodegradable nanoparticle, developed by researchers at Northwestern Medicine, offers an innovative way to halt asthma...
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Prosthetic ovary implant restores fertility in mice
1 April 2016 | By Victoria White
Researchers hope to use the technology to develop an ovary bioprosthesis that could be implanted in women to restore fertility...
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Exon skipping demonstrates success in severe form of muscular dystrophy
13 October 2015 | By Victoria White
An RNA editing technique called "exon skipping" has demonstrated preliminary success in treating Limb Girdle Muscular Dystrophy Type 2C in a new study...
