news Gene therapy bolsters Parkinson’s drug benefits in pre-clinical study 3 November 2021 | By Anna Begley (Drug Target Review) The gene therapy restored the ability of neurons to convert levodopa to dopamine and may help develop therapies to slow disease progression.
news Promising new avenue to tackle obesity-related diabetes 2 July 2021 | By Mandy Parrett (Drug Target Review) New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
news Researchers reveal 3D structure responsible for gene expression 12 March 2021 | By Victoria Rees (Drug Target Review) Researchers have produced the first 3D image of the Mediator-bound pre-initiation complex, key in the regulation of gene expression.
news Neuron damage from ALS reversed with new compound 24 February 2021 | By Victoria Rees (Drug Target Review) Scientists have developed a compound that stops the degeneration of upper motor neurons, a contributor to amyotrophic lateral sclerosis (ALS).
news New technology enables predictive design of engineered human cells 22 February 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a computer modelling programme that can produce genetic circuits for cellular engineering.
news Novel nanoscale 4D printer could be used for drug research 12 March 2020 | By Victoria Rees (Drug Target Review) A novel 4D printer has been created which can combine organic chemistry, surface science and nanolithography to design surfaces with organic or biological molecules for drug research.
news Mass spectrometry approach allows researchers to make precise protein measurements 3 March 2020 | By Victoria Rees (Drug Target Review) A new method for weighing proteins at the atom level, called individual ion mass spectrometry, has been developed by American researchers.
news New machine learning algorithm uncovers time-delayed interactions in cells 16 February 2018 | By Drug Target Review Scientists have designed a new machine learning algorithm that uses time-series data to uncover underlying biological networks.
article A new approach to Organ-on-a-Chip 11 April 2017 | By Joseph Charest | Biomedical Solutions Program Manager | Draper Draper's Joe Charest explains how synthetic organoids can lead to safer drug testing, and why organ-on-a-chip technology is the future of drug discovery...
news Manipulating HCN channels could lead to new depression treatments 12 July 2016 | By Victoria White, Digital Content Producer Using gene therapy, scientists from Northwestern Medicine have identified a target in the brain that could lead to new treatments for depression...
news TMEM230 gene shown to cause Parkinson’s disease 6 June 2016 | By Victoria White, Digital Content Producer Scientists from Northwestern University have discovered a new cause of Parkinson's disease - mutations in a gene called TMEM230...
news Breast cancer drug suppresses dangerous brain seizures 13 May 2016 | By Victoria White, Digital Content Producer Scientists also found that inhibiting oestrogen synthesis just after seizure onset strongly suppressed seizures in both sexes...
news Biodegradable nanoparticles that halt asthma 18 April 2016 | By Victoria White, Digital Content Producer A biodegradable nanoparticle, developed by researchers at Northwestern Medicine, offers an innovative way to halt asthma...
news Prosthetic ovary implant restores fertility in mice 1 April 2016 | By Victoria White Researchers hope to use the technology to develop an ovary bioprosthesis that could be implanted in women to restore fertility...
news Exon skipping demonstrates success in severe form of muscular dystrophy 13 October 2015 | By Victoria White An RNA editing technique called "exon skipping" has demonstrated preliminary success in treating Limb Girdle Muscular Dystrophy Type 2C in a new study...