A new study suggests that inflammation and blood vessel damage may be the primary causes of neurological symptoms in COVID-19 patients, instead of the virus infecting the brain.
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Engineering antibodies found in a llama, researchers have developed a potential COVID-19 therapy which they say can neutralise SARS-CoV-2.
Researchers have used a peptide called D6PV to lower triglycerides in mouse models, which could be used as a therapy for high triglyceride-induced acute pancreatitis in humans.
CAR T-cell therapy has caused quite a stir in the immunotherapy world, but it is a process that requires precision and care. Quantitative polymerase chain reaction (qPCR) has thus far been the stalwart technique for providing a check on copy numbers, but here Ping Jin explains why droplet digital PCR…
HIV is a disease still common in sub-Saharan Africa despite global research since 1982. This article delves into the trends, opportunities and key players in HIV research, exploring future possibilities for treating the disease.
Researchers have identified a set of three antibodies that they suggest could become the basis for a new antiviral treatment and inform the development of new influenza vaccines.
Researchers have created an AI model that analyses the citations of studies, predicting their potential for eventual clinical application.
Typically, early drug discovery campaigns start with the screening of chemical libraries to identify candidate chemotypes modulating a particular target and/or phenotype. Success of the primary screening depends on multiple factors related to both biology and chemistry. These include the target’s druggability, sensitivity and specificity of assay system, composition and…
Manchester University researchers have developed a high-throughput platform to analyse and study a family of enzymes that are linked to cancer...
Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD).
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
A new study by the University of Arizona (UA) suggests that revealing all the steps required to activate an enzyme called a protein kinase may help identify new ways to target cancer.
The NIH is supporting efforts to broaden biomedical scientists’ access to cryo-electron microscopy the imaging method that is revolutionising structural biology...
NIH-funded study closes in on personalised drug testing for neurological disorders...