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Researchers make key discovery involved in re-engineering of peptides

11 May 2021 | By Victoria Rees (Drug Target Review)

A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.

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Nanobody cocktail shown to block SARS-CoV-2 infection in mouse models

27 April 2021 | By Victoria Rees (Drug Target Review)

Researchers have used cryo-EM to show that a new nanobody cocktail can bind to the S protein of SARS-CoV-2, neutralising the coronavirus.

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Researchers develop model of early human embryo from skin cells

18 March 2021 | By Victoria Rees (Drug Target Review)

Scientists have created the first model of early human embryos by reprogramming fibroblasts into a blastocyst-like structures.

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β-cell regeneration discovery could pave way for diabetes treatments

16 February 2021 | By Victoria Rees (Drug Target Review)

A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.

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Researchers discover factor that triggers muscle stem cells to heal

11 February 2021 | By Victoria Rees (Drug Target Review)

In a zebrafish model, researchers have found that the protein NAPMT can trigger muscle stem cells to proliferate and heal muscle damage.

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Two novel molecules to potentially combat asthma discovered

26 January 2021 | By Victoria Rees (Drug Target Review)

Researchers have discovered that giving L-tyrosine and PCS to mice prevents lung inflammation and an allergic asthma response.

Ovarian cancer cells forming a cancer spheroid as they grow within the peptide-protein co-assembling material [Credit: Alvaro Mata].

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Novel tumour spheroids could improve ovarian cancer treatments

5 October 2020 | By Hannah Balfour (Drug Target Review)

Researchers have developed a new self-assembling three-dimensional (3D) ovarian cancer tumour model to recreate the in vitro disease more accurately.

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Researchers develop potential drug to prevent heart attacks

23 July 2020 | By Victoria Rees (Drug Target Review)

A novel drug has been created which prevented the blood clotting associated with heart attacks and strokes in pre-clinical studies.

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Link identified between COVID-19 and onset of diabetes

15 June 2020 | By Victoria Rees (Drug Target Review)

New research indicates COVID-19 could trigger the development of diabetes in healthy people, prompting experts to establish a registry for COVID-19 and diabetes data.

news

Autonomous Scanning Probe Microscopy technique developed using AI

20 March 2020 | By Victoria Rees (Drug Target Review)

Using AI and deep learning, researchers have enhanced Scanning Probe Microscopy (SPM) and made their automated resource available for scientists.

Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS)

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Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS)

9 March 2020 | By Rachael Harper (Drug Target Review)

A novel therapy, tested ex vivo, has been successful at correcting the dysfunctional body mechanism in Postural Orthostatic Tachycardia Syndrome (POTS).

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Platypus venom inspires potential new diabetes treatments

18 June 2018 | By Drug Target Review

A metabolic hormone found in the venom and gut of Australia’s iconic platypus will now be investigated for its potential to treat type 2 diabetes...

news

Study develops compound that activates tumour-fighting iNKT cells

6 April 2018 | By Drug Target Review

Researchers have discovered a significant new compound that helps to mobilise a type of T cell – invariant natural killer T (iNKT) cells – in the fight against disease.

news

BH3-mimetic drugs offer potential to treat Legionella infections

8 March 2016 | By Victoria White

Turning off BCL-XL with BH3-mimetic drugs killed Legionella-infected cells, allowing the infection to be cleared from the body...

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