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dopaminergic neuron with cell body in pink and axon and dendrites in dark blue

news

Huntington’s update: optimal treatment times and implicated molecules

28 May 2020 | By Hannah Balfour (Drug Target Review)

Two studies reveal the importance of timing in Huntington’s disease interventions and demonstrate interleukin-6 may play a protective role.

news

Specialised proteins could halt cytokine storms in COVID-19 patients

17 April 2020 | By Victoria Rees (Drug Target Review)

Researchers who developed modified proteins say this could be used in the fight against COVID-19, by tackling cytokine storms.

article

Predicting which diabetes treatments will reach clinical trials

7 April 2020 | By Victoria Rees (Drug Target Review)

Researchers at MIT have developed a mathematical model that can calculate whether diabetes treatments in pre-clinical trials will be successful in humans.

news

Novel antibiotic compound revealed through artificial intelligence screening

24 February 2020 | By Victoria Rees (Drug Target Review)

A new antibiotic compound has been identified by researchers who designed a machine-learning algorithm to screen millions of molecules.

news

Genome screen in mice reveals Huntington’s disease gene target

3 February 2020 | By Victoria Rees (Drug Target Review)

Researchers have conducted a genetic screen in mice to discover a family of genes that contributes to the development of Huntington's.

article

DTR’s news round-up 2019: the stories that defined the year

18 December 2019 | By Drug Target Review

Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.

news

Mucus has been shown to tame microbes in new study

15 October 2019 | By Rachael Harper (Drug Target Review)

Glycans, which are found in mucus, have the ability to regulate how microbes behave and could lead to new therapeutics.

news

Automation of complex synthetic biological molecules enabled by robotics

19 September 2019 | By Rachael Harper (Drug Target Review)

A new platform combines AI, flow chemistry and robotics to minimise the need for human intervention in the synthesis process.

news

Blood-brain barrier role in Alzheimer’s patients revealed by tissue model

13 August 2019 | By Rachael Harper (Drug Target Review)

A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.

news

Vaccine strategy devised to boost T-cell therapy

12 July 2019 | By Drug Target Review

A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.

news

Gut microbiome identified as cause of IBD, study finds

3 June 2019 | By Victoria Rees (Drug Target Review)

A study has detailed the change in the gut microbiome, increasing the potential for new IBD therapies.

news

Magnetic microbots could help drug-delivery nanoparticles reach their targets

3 May 2019 | By Drug Target Review

MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumour or another disease site.

news

MRI sensor to image activity deep inside the brain

22 February 2019 | By Drug Target Review

A method of imaging calcium activity that is based on magnetic resonance imaging (MRI) could help to image deep within the brain...

news

Ingestible capsule controlled wirelessly could treat diseases

13 December 2018 | By Drug Target Review

Researchers have designed a drug delivery capsule that can stay in the stomach for up to 1 month, and could sense and treat infections...

news

Repurposing wasp venom as antibiotic drugs

10 December 2018 | By Drug Target Review

Researchers have used wasp venom to create variants of a peptide that is potent against bacteria but nontoxic to human cells...

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