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Gut microbiome linked to rheumatoid arthritis prognosis

15 September 2021 | By Anna Begley (Drug Target Review)

New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.

news

Senolytic drugs reduce COVID-19 symptoms in mice, study shows

9 June 2021 | By Victoria Rees (Drug Target Review)

In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.

news

Purified exosomal product heals ischemic wounds in pre-clinical models

29 April 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that ischemic wounds in pre-clinical models which were treated with a purified exosomal product were healed.

news

LEAP proton therapy could target cancer cells that resist treatment

18 February 2021 | By Victoria Rees (Drug Target Review)

A proton therapy that targets cancer cells which are resistant to treatment has shown success, sparing surrounding healthy cells.

3D rendering of a human torso with anatomically correct lungs highlighted in orange

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T cells facilitate chronic lung injury in the elderly after viral infections, finds study

10 November 2020 | By Hannah Balfour (Drug Target Review)

After viral pneumonia in elderly mice, there is an accumulation of dysfunctional tissue-resident memory T cells in the lungs which scientists suggest may drive chronic inflammation and fibrosis.

cancer cell in yellow being attacked by white blobs - cancer drug/cell therapy

news

Study identifies potential therapeutic targets for most lethal pancreatic cancer

15 September 2020 | By Hannah Balfour (Drug Target Review)

The detailed analysis of adenosquamous cancer of the pancreas (ASCP) suggested FGFR and RORC were two promising therapeutic targets.

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Study reveals how to make pancreatic cancer chemotherapy more effective

19 September 2019 | By Victoria Rees (Drug Target Review)

Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.

news

Mutant form of Ebola could be used in vaccine development

17 September 2019 | By Victoria Rees (Drug Target Review)

A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.

news

Reprogramming stem cells using the measles virus vector

15 February 2019 | By Iqra Farooq (Drug Target Review)

A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...

news

Estradiol exerts anticancer effects in triple-negative breast cancer

5 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer...

news

Genes increasing the risk of triple-negative breast cancer identified

8 August 2018 | By Drug Target Review

Germ line genetic testing analyses blood samples and evaluates inherited genetic changes that increase the risk of certain cancers in an individual...

news

pGENMi predicts genomic features associated with drug responses

13 July 2018 | By Drug Target Review

A new system, pGENMi, could predict genomic features associated with drug responses, by identifying differences in gene expression...

news

Pixelated gene expression tool provides fast accurate results for RNA analysis

22 January 2018 | By Drug Target Review

Researchers have demonstrated how a pixelated gene expression tool can accurately measure RNA levels more quickly than existing methods allow.

news

Skin cancer on the rise – diagnosis of two types has increased

19 May 2017 | By Niamh Marriott (Drug Target Review)

New diagnoses for two types of skin cancer increased in recent years, according to a Mayo Clinic-led team of researchers.

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