news $2.6 million granted to create pan-coronavirus vaccine 25 October 2021 | By Anna Begley (Drug Target Review) The La Jolla Institute for Immunology and Brigham and Women's Hospital will collaborate to develop a pan-coronavirus vaccine.
news Specific gene implicated in cardiovascular calcification 30 October 2019 | By Fraser Owen (Drug Target Review) Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
news Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours 10 April 2019 | By Drug Target Review Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
news Tau protein disrupts molecular transport in neurons in Alzheimer’s 5 September 2018 | By Iqra Farooq (Drug Target Review) Researchers have discovered how the tau protein associated with Alzheimer's affects molecular transport and a nucleporin called Nup98...
news Cellular reprogramming promotes muscle regeneration in injured mice 9 May 2018 | By Drug Target Review Scientists have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells...
news Researchers create anti-inflammatory antibodies to treat autoimmune disease 22 December 2017 | By Steve Bremer (Drug Target Review) Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
news Tumour cell biology reveals characteristic that causes metastasis 30 November 2017 | By Drug Target Review A collaborative team of researchers in the US have uncovered characteristics of tumour cells that are linked to cancer metastasis.
news Lung tumours communicate with bones to progress disease 30 November 2017 | By Drug Target Review Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
news Mn-PyC3A MRI contrast agent may be a safer alternative to gadolinium 16 November 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a potential alternative to gadolinium-based contrast agents for magnetic resonance imaging...
news Molecular pathway offers treatment targets for pulmonary fibrosis 16 November 2017 | By Dr Zara Kassam (Drug Target Review) A study has identified a molecular pathway that appears to be critical to the development of fibrosis...
news Researchers produce the first draft cell atlas of the small intestine 8 November 2017 | By Dr Zara Kassam (Drug Target Review) By surveying gene expression, researchers have created a reference atlas for understanding the biology of inflammatory bowel disease and food allergies, among other conditions...
news New techniques give blood biopsies greater promise 6 November 2017 | By Dr Zara Kassam (Drug Target Review) Improved methods validate the use of blood samples for studying patients' cancer genomes
news Mature B lymphocytes accelerate the healing of acute and chronic wounds 27 October 2017 | By Dr Zara Kassam (Drug Target Review) Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
news Gene transcription in CD8 T cells differentiates chronic from resolving HCV 17 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
news Lymph node metastases may not always be source of cancer’s spread 7 July 2017 | By Niamh Marriott (Drug Target Review) A study led has found that the model for the spread of carcinoma - from the primary tumour, to nearby lymph nodes, to other organs - may not apply in all cases.
