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$2.6 million granted to create pan-coronavirus vaccine
The La Jolla Institute for Immunology and Brigham and Women's Hospital will collaborate to develop a pan-coronavirus vaccine.
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Massachusetts General Hospital
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Specific gene implicated in cardiovascular calcification
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
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Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours
Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
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Tau protein disrupts molecular transport in neurons in Alzheimer’s
Researchers have discovered how the tau protein associated with Alzheimer's affects molecular transport and a nucleporin called Nup98...
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Cellular reprogramming promotes muscle regeneration in injured mice
Scientists have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells...
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Researchers create anti-inflammatory antibodies to treat autoimmune disease
Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
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Tumour cell biology reveals characteristic that causes metastasis
A collaborative team of researchers in the US have uncovered characteristics of tumour cells that are linked to cancer metastasis.
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Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
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Mn-PyC3A MRI contrast agent may be a safer alternative to gadolinium
Researchers have developed a potential alternative to gadolinium-based contrast agents for magnetic resonance imaging...
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Molecular pathway offers treatment targets for pulmonary fibrosis
A study has identified a molecular pathway that appears to be critical to the development of fibrosis...
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Researchers produce the first draft cell atlas of the small intestine
By surveying gene expression, researchers have created a reference atlas for understanding the biology of inflammatory bowel disease and food allergies, among other conditions...
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New techniques give blood biopsies greater promise
Improved methods validate the use of blood samples for studying patients' cancer genomes
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Mature B lymphocytes accelerate the healing of acute and chronic wounds
Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
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Gene transcription in CD8 T cells differentiates chronic from resolving HCV
Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
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Lymph node metastases may not always be source of cancer’s spread
A study led has found that the model for the spread of carcinoma - from the primary tumour, to nearby lymph nodes, to other organs - may not apply in all cases.
