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Novel technique reveals how TB antibiotics reach their targets
Researchers have used a new method to understand how antibiotics fight TB, which can guide future drug developments.
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Francis Crick Institute
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Flow Cytometry In-Depth Focus 2018
Flow cytometry has played a key role in drug development, largely due to its ability to measure up to twenty parameters on single cells or particles suspended in a fluid stream. Conor Fitzpatrick discusses how the rise of high-throughput flow cytometry has contributed to the advancements in drug discovery...
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Genes linking Alzheimer’s and Down syndrome discovered
Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...
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Gene signature holds promise for early detection of active TB
A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.
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Alpha-synuclein clumps promote Parkinson’s progression
Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...
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Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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The spreading mechanism of malaria parasites provides new drug target
A team of researchers in the UK have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, thus offering potential new treatment targets.
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cDC1 cells could improve cancer immunotherapy
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...
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CRISPR used to identify drug target for bowel cancer
CRISPR used to identify a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies...
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Genome editing reveals a role for OCT4 in human embryogenesis
Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...
