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Dana-Farber Cancer Institute

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Novel inhibitor blocks myeloma cancer cell growth in mouse model

18 May 2021 | By Victoria Rees (Drug Target Review)

Having identified the histone demethylase KDM5A as a multiple myeloma target, researchers developed a KDM5 inhibitor to treat the cancer.

news

Researchers identify lead compounds for treatment of telomere diseases

23 April 2020 | By Victoria Rees (Drug Target Review)

Researchers investigating telomere dieases such as dyskeratosis congenita have found lead compounds that reverse cellular ageing in mouse models of the condition.

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Dozens of anti-cancer compounds revealed by screening existing drugs

21 January 2020 | By Victoria Rees (Drug Target Review)

Researchers have screened thousands of existing drug molecules against cancer cell lines to discover almost 50 compounds that combat the condition.

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Sequencing offers clues to progression toward multiple myeloma

11 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have carried out the largest genomic analysis of patients with SMM to explain the biology of the disease and how it unfolds through time...

Genomic analysis unravels complexities of the most common form of lymphoma

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Genomic analysis unravels complexities of the most common form of lymphoma

3 May 2018 | By Drug Target Review

Genomic analysis has shown a better framework for understanding lymphoma’s many forms and will help to predict individual patient outcomes and guide personalised treatment.

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New techniques give blood biopsies greater promise

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

Improved methods validate the use of blood samples for studying patients' cancer genomes

news

Blood test developed to diagnose ovarian cancer

1 November 2017 | By Dr Zara Kassam (Drug Target Review)

Non-invasive diagnostic tool measures circulating microRNAs to predict ovarian cancer with specificity...

news

Researchers find key molecule that could lead to new anaemia therapies

17 May 2017 | By Niamh Marriott (Drug Target Review)

Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.

news

Role of let-7 in neuroblastoma offers a new angle on treatment

8 July 2016 | By Victoria White, Digital Content Producer

A study has found that let-7 plays a central role in curbing neuroblastoma and could focus efforts to find a targeted, nontoxic alternative to chemotherapy...

news

Newly identified pathway could lead to obesity treatments

30 June 2016 | By Victoria White, Digital Content Producer

Scientists identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat...

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