article Five developments in oncology targets 30 July 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores some of the newest oncologic drug targets, including those for glioblastoma, lung cancer and breast cancer.
news Researchers find drug improves cancer immunotherapy in mice 3 March 2020 | By Victoria Rees (Drug Target Review) A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.
news Update on the development of new novel cancer immunotherapy 24 May 2019 | By Drug Target Review The SCIB2 vaccine is to to be administered using new nanoparticle formulation in planned Phase 1/2 clinical trial.
news Anticancer drug as an alternative to liver transplant 17 August 2018 | By Drug Target Review Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
news Inhibiting NAT10 provides therapeutic target for HGPS 30 April 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford progeria syndrome...
news New class of drugs could help tackle treatment-resistant cancers 12 April 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...
news cDC1 cells could improve cancer immunotherapy 12 February 2018 | By Dr Zara Kassam (Drug Target Review) Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...
news Scientists halt breast cancer spread 9 February 2018 | By Drug Target Review Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.
news DNA sequencing could open up new drug indications for rare cancers 8 September 2017 | By Dr Zara Kassam (Drug Target Review) A network of hospitals have systematically collected biopsies from metastatic cancer patients in order to create a global database...
news Anti-hormone therapy reduces recurrence of prostate cancer 5 September 2017 | By Dr Zara Kassam (Drug Target Review) British scientists have investigated the impact of anti-hormone therapy on patients with prostate cancer...
news New imaging technique may predict the of spread breast cancer 16 August 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a radioactive ‘tracer’ molecule to detect myeloid-derived suppressor cells’ accumulating in the lung in preparation for the arrival of breast cancer cells...
news Novel immuno-oncology treatment for patients with advanced solid tumours 10 August 2017 | By Dr Zara Kassam (Drug Target Review) An experimental immuno-oncology treatment will move into early phase clinical trials for patients with advanced solid tumours...
news Hamish Ryder joins Drug Target Review Advisory Board 31 July 2017 | By Steve Bremer (Drug Target Review) Prior to joining CRT-DL, Dr Ryder held positions in pharmaceutical and biotech companies for over 20 years ...
news Simple test predicts return of bladder cancer 12 July 2017 | By Niamh Marriott (Drug Target Review) Scientists have devised a simple test for an earlier and more accurate warning of returning bladder cancer than existing methods, according to new research...
news Cancer Research UK sets out latest £20m grand challenges 27 June 2017 | By Sarah Wills (Drug Target Review) Cancer Research UK has launched the second phase of its global Grand Challenge by announcing eight new questions – identified as some of the biggest barriers to making progress against cancer – and inviting the world’s top scientists to come together with new proposals to tackle them.