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Brigham and Women's Hospital (BWH)

Glowing yellow pancreas in human torso - idea of diabetes, where pancreatic beta cells are destoryed

news

Next-generation diabetes prodrugs identified using novel screening platform

17 December 2020 | By Hannah Balfour (Drug Target Review)

Researchers engineered the Disque Platform, a high-fidelity culture system, to enable them to screen drugs able to promote β cell proliferation.

news

Novel GI tract coating could deliver drugs, aid digestion or control obesity

27 August 2020 | By Hannah Balfour (Drug Target Review)

The developers of a temporary coating which adheres to the small intestine demonstrated it could be modified to deliver drugs, aid digestion and stop absorption of glucose.

news

microRNA could lead to new methods to treat multiple sclerosis

27 November 2019 | By Rachael Harper (Drug Target Review)

In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.

news

miR-132 offers hope for novel Alzheimer’s treatments

3 August 2018 | By Dr Zara Kassam (Drug Target Review)

The study of neuroprotective microRNAs like miR-132 may lead to new avenues for treating Alzheimer's disease and other tau pathologies...

news

Cancer protein NEDD9 plays a critical role in PAH

14 June 2018 | By Dr Zara Kassam (Drug Target Review)

Study identifies cancer protein as a target for treating fibrosis of the lung arteries with direct implications for patients with pulmonary arterial hypertension...

news

Mature B lymphocytes accelerate the healing of acute and chronic wounds

27 October 2017 | By Dr Zara Kassam (Drug Target Review)

Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...

news

Underlying genetic causes of congenital heart disease identified

9 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...

news

New genetic cause discovered for photosensitive blood disorder

15 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have uncovered a new genetic cause for erythropoietic protoporphyria...

news

Researchers find key molecule that could lead to new anaemia therapies

17 May 2017 | By Niamh Marriott (Drug Target Review)

Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.

news

Nanoparticles used to deliver RNAi agents to thyroid cancer tumours

20 June 2016 | By Victoria White, Digital Content Producer

Researchers have developed an innovative nanoplatform that allows them to effectively deliver RNAi agents to the sites of cancer and suppress tumour growth...

news

Evidence that gut microbes can influence brain inflammation

9 May 2016 | By Victoria White, Digital Content Producer

New research suggests that gut microbes may remotely influence the activity of cells in the brain that are involved in inflammation and neurodegeneration...

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