Drug could prevent cognitive decline associated with brain tumour radiation 16 April 2020 | By Hannah Balfour (Drug Target Review) Researchers demonstrated NSPP completely prevented cognitive decline in mice treated with radiation for patient-derived glioblastomas.
Stem cells in COPD patient lungs revealed as drug target for condition 16 April 2020 | By Victoria Rees (Drug Target Review) There are heightened levels of abnormal stem cells in the lungs of COPD patients, presenting a drug target that researchers are screening compounds against.
Celltrion selects 14 lead monoclonal antibodies for COVID-19 treatment 16 April 2020 | By Victoria Rees (Drug Target Review) After screening 300 antibodies, Celltrion has identified the 14 most powerful that could potentially combat the COVID-19 coronavirus.
Researchers reveal how remdesivir prevents COVID-19 viral replication 15 April 2020 | By Victoria Rees (Drug Target Review) According to a new study, the drug remdesivir is a very potent inhibitor for coronavirus polymerases - demonstrating its potential for combatting COVID-19.
COVID-19 Drug Repurposing Database made open-access by Excelra 15 April 2020 | By Hannah Balfour (Drug Target Review) The enterprise revealed that it has made its COVID-19 Drug Repurposing Database open-access to aid in the search for an effective therapeutic.
Novel 3D imaging technology could improve fluorescence microscopy 15 April 2020 | By Victoria Rees (Drug Target Review) A new technique called Coded Light-sheet Array Microscopy (CLAM) has been developed by researchers to improve 3D imaging of living specimens.
Plant bio-factories contributing to the COVID-19 fight 15 April 2020 | By Hannah Balfour (Drug Target Review) Researchers have made the genome of the Nicotiana benthamiana plant, a commonly used bio-factory organism, public to aid in COVID-19 vaccine production.
Researchers release 21 openly available SARS-CoV-2 genome sequences 14 April 2020 | By Hannah Balfour (Drug Target Review) Austrian researchers reveal the first 21 SARS-CoV-2 viral genomes as part of their project to aid in international understanding of how the virus causing COVID-19 mutates.
Label-free array system market to be worth $1,600 million by 2025, study finds 14 April 2020 | By Victoria Rees (Drug Target Review) The global label-free array system market will grow at a compound annual growth rate of 7.44 percent in the forecast period, says new research.
Main COVID-19 protease revealed, enabling screening of potential drugs 14 April 2020 | By Victoria Rees (Drug Target Review) Chinese researchers who determined the crystal structure of the COVID-19 protease Mpro used this information to screen over 10,000 compounds to combat the coronavirus.
Disrupting tumour pH levels could be novel strategy to fight pancreatic cancer 9 April 2020 | By Victoria Rees (Drug Target Review) By targeting NHE7 transport proteins in pancreatic tumours, researchers caused the pH of cancer cells to become acidic, combatting the condition.
New imaging technique developed to study fungi 9 April 2020 | By Victoria Rees (Drug Target Review) German researchers have developed a novel imaging technique called expansion microscopy (ExM) to investigate fungi samples.
Wallflower genome analysed to reveal how plants biosynthesise therapeutic compounds 9 April 2020 | By Victoria Rees (Drug Target Review) Researchers have used the genome of Erysimum cheiranthoides (wormseed wallflower) to understand how plants biosynthesise cardenolides.
Human lung epithelium model being tested as a platform for COVID-19 research 9 April 2020 | By Hannah Balfour (Drug Target Review) The developers of the lung epithelium model plan to investigate whether SARS-CoV-2 can infect and replicate in the model to assess whether it could be used in the fight against COVID-19.
Transplanted reprogrammed skin cells repair stroke-damaged rat brains 9 April 2020 | By Hannah Balfour (Drug Target Review) Skin cells reprogrammed into nerves and transplanted into the stroke-damaged rat brains formed functional connections that restored mobility and touch sensation.
