Blood test could identify those most at risk from COVID-19 22 May 2020 | By Hannah Balfour (Drug Target Review) Collaborative research has revealed two hallmarks of COVID-19 infection associated with more severe symptoms that can be identified by a blood test.
Novel method enables mapping of signalling within living cells 22 May 2020 | By Hannah Balfour (Drug Target Review) A novel microscopy method has enabled researchers to study the flow of signalling information within living cells and could enhance our understanding of cancer metastasis.
White blood cells as a novel early indicator of vaccine efficacy 21 May 2020 | By Hannah Balfour (Drug Target Review) Researchers demonstrate that a subpopulation of circulating white blood cells can act as an early indicator of vaccine efficacy, with potential implications for COVID-19 drug development.
Protective immunity to SARS-CoV-2 shown in non-human primates 21 May 2020 | By Hannah Balfour (Drug Target Review) Macaques were protected against SARS-CoV-2 infection both after an initial infection and vaccination with a prototype vaccine, researchers suggest humans could respond similarly.
Human enzymes could be driving COVID-19 evolution, suggest researchers 21 May 2020 | By Hannah Balfour (Drug Target Review) Post-infection genome editing could be the cause of mutations in the SARS-CoV-2 virus responsible for the COVID-19 pandemic, driving its evolution.
Antibody named S309 from SARS patient shows promise against COVID-19 20 May 2020 | By Victoria Rees (Drug Target Review) An antibody called S309, identified in a blood sample from a SARS patient, inhibits related coronaviruses, including SARS-CoV-2, researchers have found.
Researchers use algorithm to design articifical proteins for vaccines 20 May 2020 | By Victoria Rees (Drug Target Review) Scientists have developed a method for designing artificial proteins that tell the immune system which antibodies to produce so could enhance vaccine design.
Analysis of immune response to SARS-CoV-2 gives hope for COVID-19 vaccines 19 May 2020 | By Victoria Rees (Drug Target Review) A detailed analysis of the body's immune response to COVID-19 has revealed that it can recognise SARS-CoV-2 in many ways, meaning vaccines can be used to stop the spread of the virus.
Novel microfluidic and sequencing method enables epigenetic studies 19 May 2020 | By Victoria Rees (Drug Target Review) A new microfluidic technology has been developed which can profile histone modifications with as few as 100 cells per assay.
Study finds coronaviruses do not readily induce cross-protective antibody responses 19 May 2020 | By Victoria Rees (Drug Target Review) Researchers have found that antibodies produced in response to SARS and COVID-19 are cross-reactive, but not cross protective in cells and mice.
Lipid mediators suggested as potential COVID-19 inflammation treatment 18 May 2020 | By Victoria Rees (Drug Target Review) A new article has outlined the body's inflammatory response to COVID-19 infection, saying that lipid mediators derived from omega-3 fatty acids could prevent life-threatening inflammation.
Adding RPL6 protein to vaccine prevents malaria in mice, find researchers 18 May 2020 | By Victoria Rees (Drug Target Review) Researchers have shown that adding the RPL6 protein to malaria vaccines was successful at protecting mice against the condition.
Oxford University and NIH COVID-19 vaccine shows success in rhesus macaques 18 May 2020 | By Victoria Rees (Drug Target Review) A vaccine currently in Phase I clinical trials was effective at inducing immune responses against SARS-CoV-2 in mice and rhesus macaques.
Scientists stress need for research into COVID-19 symptom treatment 15 May 2020 | By Victoria Rees (Drug Target Review) In a new article, researchers highlight the need for treatments to combat the potentially lethal overreaction of the immune system in the progression of COVID-19.
Researchers observe how SARS-CoV-2 changes human cells after infection, revealing drug targets 15 May 2020 | By Victoria Rees (Drug Target Review) Using mass spectrometry, researchers have shown how human cells are changed by infection from SARS-CoV-2, allowing the team to identify drug targets to prevent viral reproduction.
