Oncodesign and BMS enter drug discovery collaboration
5 January 2016 | By Victoria White
Oncodesign and Bristol-Myers Squibb have entered into a strategic collaboration to discover, develop and commercialise novel macrocyclic compounds...
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Renova expands its robust gene therapy intellectual property portfolio
5 January 2016 | By Victoria White
Renova and Research Development Foundation (RDF) have entered into a worldwide exclusive license agreement for RDF's portfolio of urocortin and stresscopin genes, as well as select peptides and proteins...
Nanobiotix to explore NBTXR3 in immuno-oncology
5 January 2016 | By Victoria White
NBTXR3 is a radio-enhancer, using a physical mode of action to destroy cancer cells in any solid tumours, in combination with radiotherapy...
AIC649 shows potential to induce functional cure in preclinical HBV study
5 January 2016 | By Victoria White
AIC649 is an inactivated parapoxvirus ovis particle preparation with distinct immunological activities including regulated cytokine release and activation of T-cell responses...
CanSAR cancer drug discovery database goes 3D
4 January 2016 | By Victoria White
The updated canSAR database will allow scientists working in the UK and across the globe to design new cancer treatments more effectively...
Cellectis files clinical trial application for UCART19 in leukaemia
4 January 2016 | By Victoria White
UCART19 is a potential best-in-class allogeneic Talen gene edited T-cell product for treatment of CD19 expressing haematological malignancies...
Baxalta and Symphogen enter immuno-oncology collaboration
4 January 2016 | By Victoria White
As part of the collaboration agreement, Symphogen is to receive $175 million upfront, in addition to potential future milestone payments and royalties...
Memory drug BPN14770 moves into Phase 1 safety trial
4 January 2016 | By Victoria White
BPN14770 may be a possible treatment for dementia and Alzheimer’s disease with less potential for side effects than rolipram...
Vertex and Genomics enter target pathway collaboration
4 January 2016 | By Victoria White
Vertex Pharmaceuticals is to use Genomic’s integrated database and state-of-the-art analysis tools to identify target therapeutic pathways...
Drug generates exciting results in metastatic breast cancer models
23 December 2015 | By Victoria White
A team at CSHL has announced preclinical data suggesting the promise of a novel drug directed against a novel target in malignant mammary tumours...
ARA 290 improves islet cell transplantation outcome in Type 1 diabetes
23 December 2015 | By Victoria White
ARA 290 is a first-in-class synthetic peptide designed to activate the innate repair mechanism in the setting of tissue injury...
Study identifies MDSCs as possible prostate cancer target
22 December 2015 | By Victoria White
MDSCs are immune cells that “expand” when faced with cancer, inflammation or infections, giving them the unique ability to suppress the body’s T-cell response to disease...
Enhancing proteasome activity may prevent dementia
22 December 2015 | By Victoria White
A study suggests that enhancing proteasome activity with drugs during the early stages of Alzheimer’s may prevent dementia and reduce damage to the brain...
IMI launches Calls to advance drug development in Ebola, Alzheimer’s and AMD
22 December 2015 | By Victoria White
The IMI has launched two Calls for proposals that will advance drug development in Ebola, childhood cancers, neurological disorders, and eye disease...
Mimetas awarded funding for organ-on-a-chip neurotoxicity models
22 December 2015 | By Victoria White
The funding is awarded in the context of the Neuratect CRACK IT Challenge to support development of better predictive, high-throughput, animal-free models for neurotoxicity of medicines and chemicals...
