Histone 1, the guardian of genome stability
Researchers have explained for the first time that the suppression of histone 1 causes cell damage and genomic instability...
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Two-step process leads to cell immortalisation and cancer
New research, has studied the immortalisation process using genome-engineered cells...
Novel immunotherapy technology for prostate cancer
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
Researchers find switch that turns on immune cells tumour-killing ability
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
Researchers identify powerful pain reliever
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
Fostering a culture of innovation to drive growth
At Charles River, we are passionate about fostering innovation as our commitment to ensure clients are provided with the most efficient path to market...
New imaging technique may predict the of spread breast cancer
Researchers have developed a radioactive ‘tracer’ molecule to detect myeloid-derived suppressor cells’ accumulating in the lung in preparation for the arrival of breast cancer cells...
Potential broad-spectrum antiviral discovery for herpes virus
Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...
New synthetic polio vaccine candidate
A collaborative team of scientists have developed a novel synthetic vaccine with a method grown in plants that uses virus-like particles...
New genetic analysis reveals early diagnosis for breast cancer
Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...
Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
£2m collaboration to focus on gene and cell therapy
A leading gene and cell therapy group has announced a collaboration focusing on gene and cell therapy manufacturing..
From cancer evolution to personalised therapies
A research team have studied how alterations in a tumour depend on each other and how these dependencies determine cancer evolution...
Blood test to transform the way cancer is monitored and treated
Scientists have described a new type of test that can detect genetic mutations in minute amounts of DNA...
Paediatric ulcerative colitis drug gets orphan designation
The U.S. Food and Drug Administration has granted an orphan-drug designation to cobitolimod for the treatment of ulcerative colitis in pediatric patients...
