Alpha-1 antitrypsin deficiency shows promise in rare liver disease 20 October 2017 | By Dr Zara Kassam (Drug Target Review) Nuclease-free gene editing has been found to correct mutated cells ...
Key psychiatric drug target comes into focus 20 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have reported a major step forward towards designing more powerful psychiatric drugs with fewer side effects...
Discovery lights path for Alzheimer’s research 19 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers identify binding site on the amyloid beta peptide that could facilitate better drugs to treat the disease...
Phenogenetic map created for stem cell models of neurological diseases 19 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...
Peripheral T-cell lymphoma linked to textured breast implants 19 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have analysed a rare peripheral T-cell lymphoma that may develop as a result of breast implants...
dCA accelerates HIV-1 suppression in chronically infected cells 18 October 2017 | By Dr Zara Kassam (Drug Target Review) Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...
Synthetic compound targets energy generation of metastatic cancer cells 18 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a synthetic compound that targets the enzyme FerT, thereby killing metastatic cells...
Cryo-MOST approach maps whole-brain changes in Alzheimer’s disease 18 October 2017 | By Nic Losardo (Drug Target Review) Micron-level, 3-D visualisation of protein deposits found in Alzheimer's disease could speed development of new treatments...
CRISPR used to identify drug target for bowel cancer 17 October 2017 | By Dr Zara Kassam (Drug Target Review) CRISPR used to identify a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies...
Gene transcription in CD8 T cells differentiates chronic from resolving HCV 17 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
Macrophages play critical role in sustained delivery of MD therapy 16 October 2017 | By Dr Zara Kassam (Drug Target Review) Inflammatory cells retain drug after it disappears from circulation, improving delivery to regenerating muscle cells...
MS risk in children detected with MRI brain scans 16 October 2017 | By Nic Losardo (Drug Target Review) MRIs can reveal changes in the brain associated with MS before the clinical symptoms of the disease appear in children...
Antibiotic resistance genes identified 16 October 2017 | By Dr Zara Kassam (Drug Target Review) By analysing large volumes of DNA data, researchers have identified 76 new types of antibiotic-resistant genes...
Modified CRISPR technique used to combat Parkinson’s disease 13 October 2017 | By Dr Zara Kassam (Drug Target Review) Biological engineers identify genes that protect against protein linked to Parkinson's disease...
A3G protein fights HIV as monomer and dimer 13 October 2017 | By Dr Zara Kassam (Drug Target Review) A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...
