New machine learning algorithm uncovers time-delayed interactions in cells 16 February 2018 | By Drug Target Review Scientists have designed a new machine learning algorithm that uses time-series data to uncover underlying biological networks.
CRISPR-Cas12a enables accurate disease diagnostics 15 February 2018 | By Dr Zara Kassam (Drug Target Review) DETECTR system allows quick, one-step detection and diagnosis of disease, infection...
Single-cell RNA sequencing provides molecular atlas to study brain diseases 15 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have detailed a molecular atlas of the cells that form the brain's blood vessels and the life-essential blood-brain barrier providing clues to which cell types are involved in different diseases...
BX795 molecule clears HSV-1 infection in human corneal cells 15 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers at the have identified a small drug molecule that can clear the herpes simplex virus-1 infection, making it a promising potential option for patients who have developed resistance...
Explore next generation therapeutics and ATMPS in May 15 February 2018 | By Terrapinn The 13th annual World Advanced Therapies & Regenerative Medicine Congress brings together 1000+ attendees and explores the rapidly developing world of next generation therapeutics and ATMPS.
Osimertinib resistance explained by computer simulations 15 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
Depleting BACE1 reverse the formation of amyloid plaques in Alzheimer’s disease 14 February 2018 | By Dr Zara Kassam (Drug Target Review) A team of researchers from the have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's disease...
Cardiac imaging analysis predicts success of Afib treatment 14 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers report the successful use of heart imaging to predict the benefit or futility of catheter ablation...
Study uncovers molecular events that reveal pathway toward heart disease therapy 14 February 2018 | By Drug Target Review Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.
Novel classification can lead to new ways to diagnose and treat cancer 14 February 2018 | By Drug Target Review A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.
RT-QuIC assay adapted to test for Parkinson’s and dementia with Lewy bodies 14 February 2018 | By Dr Zara Kassam (Drug Target Review) NIH scientists have modified an assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies...
Huntington’s disease provides new cancer weapon 13 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...
Small molecule could make a big difference for arthritis patients 13 February 2018 | By Drug Target Review Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
Molecular therapy restores nerve insulation on peripheral nerves 13 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have described an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort...
cDC1 cells could improve cancer immunotherapy 12 February 2018 | By Dr Zara Kassam (Drug Target Review) Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...
