Scientists show combined immunotherapy treatment is effective against advanced melanoma 28 August 2018 | By Drug Target Review Study in the U.S. demonstrates successful treatment of advanced melanoma and metastatic cancer using a new bacteria-like agent combined with an immunotherapy drug.
The molecular link between ageing and neurodegeneration 28 August 2018 | By Drug Target Review Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
NanoMIPs efficiently target and eliminate cancer cells 24 August 2018 | By Dr Zara Kassam (Drug Target Review) A joint research team has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs...
Powerful molecules provide new findings about Huntington’s disease 23 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...
Experimental drug targets cancers associated with Epstein-Barr virus 23 August 2018 | By Iqra Farooq (Drug Target Review) An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...
AI system detects cancer tumours missed by conventional diagnostics 23 August 2018 | By Iqra Farooq (Drug Target Review) Computer engineers have 'taught' a computer to identify tiny specs of lung cancer in CT scan images, often missed by radiologists...
New assay to detect genetic abnormalities in sarcomas 22 August 2018 | By Dr Zara Kassam (Drug Target Review) A new study describes an assay, anchored multiplex PCR (AMP)-based targeted next-generation-sequencing (NGS), with superior diagnostic utility compared to conventional techniques...
Modified-RNA vaccine elicits protective response against influenza 22 August 2018 | By Dr Zara Kassam (Drug Target Review) A universal flu vaccine that protects people against most influenza strains is one step closer to reality...
Blood test may identify cancer patients who won’t respond to immunotherapy 22 August 2018 | By Dr Zara Kassam (Drug Target Review) Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test...
Researchers develop biosensor with real-time oxygen monitoring 21 August 2018 | By Iqra Farooq (Drug Target Review) In a study, researchers have developed a biosensor concept using organs-on-a-chip to measure the levels of oxygen in real-time...
Vitamin B3 could potentially treat kidney injury 21 August 2018 | By Drug Target Review A team of researchers have identified vitamin B3 can increase levels of NAD+, which is decreased in those with acute kidney injury...
Research team develops predictor for immunotherapy response in melanoma 21 August 2018 | By Drug Target Review Researchers have developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors...
Cocaine relapse is reversed with BDNF microinjections in the brain 20 August 2018 | By Drug Target Review Researchers have discovered that a very common protein in the brain has an additional significant role in addiction relapse...
Compound with selectivity for cancer cells without p53 identified 20 August 2018 | By Iqra Farooq (Drug Target Review) The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...
GC4419 could prevent debilitating side effect of cancer treatment 20 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
