Artificial intelligence method generates synthetic active ingredients 9 July 2021 | By Anna Begley (Drug Target Review) A team in Switzerland have demonstrated how artificial intelligence could be used in the search for new pharmaceutical agents.
Anticoagulant drug a possible strategy to treat COVID-19 variants 8 July 2021 | By Anna Begley (Drug Target Review) Researchers in Australia have discovered a new site on the COVID-19 Spike protein that could be targeted by an anticoagulant drug.
Metabolic pathway could potentially enhance vaccine effectiveness 8 July 2021 | By Anna Begley (Drug Target Review) A metabolic control pathway that regulates T follicular helper cells could enhance vaccine effectiveness, including those that protect against COVID-19.
Protein activation discovery could widen access to cancer immunotherapy 8 July 2021 | By Anna Begley (Drug Target Review) The activation of the protein p53 was shown to boost immune responses against cancer tumours in mice in a new study, potentially widening access to immunotherapy.
High-throughput method developed for single-cell metabolic profiling 7 July 2021 | By Anna Begley (Drug Target Review) Scientists have presented a new method for generating the metabolic profiles of cells which could answer questions on conditions such as cancer and liver disease.
‘Zombie cells’ may hold answer to spinal cord injury recovery 7 July 2021 | By Anna Begley (Drug Target Review) Portuguese researchers propose targeting senescent cells in zebrafish and mammals could lead to developments in human spinal cord injury repair.
New microscopy method could lead to advancements in cell biology 7 July 2021 | By Anna Begley (Drug Target Review) Researchers at UT Southwestern have invented a novel microscopy method that could open new avenues of advanced microscopy.
Mefloquine identified as promising potential drug to combat COVID-19 6 July 2021 | By Anna Begley (Drug Target Review) Researchers in Japan propose that the antimalarial drug mefloquine could be repurposed to effectively treat SARS-CoV-2.
Novel gene therapy for heart failure moves closer to clinic 6 July 2021 | By Anna Begley (Drug Target Review) New research by US institutions in pigs shows that knocking down a particular signalling pathway after heart failure renews heart tissue.
Scientists publish guide for creating mouse-human chimeric embryos 6 July 2021 | By Victoria Rees (Drug Target Review) Researchers have published a step-by-step protocol on how to produce millions of mature human cells in a chimeric mouse embryo.
Potential COVID-19 antivirals revealed in large-scale drug analysis 5 July 2021 | By Anna Begley (Drug Target Review) Drug analysis at the Francis Crick Institute and University of Dundee has revealed 15 potential antivirals that could lead to new COVID-19 treatments.
Nanosized molecules inhibit formation of plaques related to Alzheimer’s 5 July 2021 | By Victoria Rees (Drug Target Review) In brain tissues, researchers have shown that two different nanosized polyoxoniobate molecules can inhibit the assembly of amyloid plaques.
Promising new avenue to tackle obesity-related diabetes 2 July 2021 | By Mandy Parrett (Drug Target Review) New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
Bioactivity information of one million molecules compiled 1 July 2021 | By Victoria Rees (Drug Target Review) Using deep machine learning, researchers have completed the activity profiles, from chemistry to clinical level, for one million molecules.
Natural killer cell immunotherapy shows promise against melanoma 30 June 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that natural killer cell immunotherapy effectively treated mice harbouring human melanoma tumours.
