Mouse model for diabetic kidney disease suggests role for immune and inflammatory pathways
Scientists have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy...
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Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
Magnetically controlled thrombolytic passed preclinical trials
ITMO University scientists have used nanoparticles and magnetic waves to localise drug delivery in animal models, resulting in no side effects...
Drug repurposing using off patent drugs as antifungals
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
Sensory neurons can be used to discover therapies for ALS
New approach for testing for ALS may be useful to reverse debilitating disease...
Brain activity pattern may be early sign of schizophrenia
In a study that might enable earlier diagnosis, neuroscientists find abnormal brain connections that can predict the onset of psychotic episodes...
Disrupting quinolones to prevent antibiotic resistance
Disrupting the communication between bacteria and quinolone signalling can inhibit the the production of toxins and virulence factors...
Anti-inflammatory bacterial protein discovered in zebrafish
An anti-inflammatory bacterial protein discovered in zebrafish could lead to the discovery of anti-inflammatory proteins within humans...
Gene responsible for hair loss discovered
The gene responsible for hair loss caused by the hypotrichosis simplex has been discovered by researchers at the University of Bonn...
Scientists pinpoint mechanism by which mutant p53 protein promotes cancer
Scientists in Australia have discovered how the most important gene in preventing cancer, TP53, is hampered in its tumour-fighting efforts by mutant p53 proteins.
Making old antibiotics work better using r8
A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...
P2K system could resolve bottlenecks in drug research
Researchers have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests...
Parasitic worm study predicts potential drug targets and drugs
The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...
Potential of gene therapy for neurological disorders
Gene therapy could be effective in numerous neurological conditions and could transform the lives of patients with these incurable diseases...
NGLY1 protein identified as potential target for melanoma treatment
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
