USP15 enzyme could have role in the future treatment of cancer 15 March 2019 | By Drug Target Review Researchers have found that the enzyme USP15 could potentially lead to new therapies for both breast and pancreatic cancer...
Non-invasive imaging for small airway lung disease 14 March 2019 | By Iqra Farooq (Drug Target Review) A non-invasive method of imaging tiny bronchioles in the lungs of chronic obstructive pulmonary disease means patients could detect the disease earlier...
Machine-learning model to analyse protein sequences 14 March 2019 | By Iqra Farooq (Drug Target Review) A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
Optical imaging technique to detect tiny tumours 8 March 2019 | By Iqra Farooq (Drug Target Review) A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
Potential EBV-associated cancer treatment in small molecule inhibitors 7 March 2019 | By Iqra Farooq (Drug Target Review) A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
Salamander gene partnerships could help spinal cord regeneration 6 March 2019 | By Iqra Farooq (Drug Target Review) Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori 5 March 2019 | By Iqra Farooq (Drug Target Review) Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
Genomics to match treatments to pancreatic cancer patients 4 March 2019 | By Nic Losardo (Drug Target Review) Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
Protein marker in response to brain cancer therapy 1 March 2019 | By Fraser Owen (Drug Target Review) An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
Genetic study confirms that numerous genes contribute to Tourette’s syndrome 1 March 2019 | By Iqra Farooq (Drug Target Review) A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
Colon cancer pathway discovery could lead to targeted therapies 28 February 2019 | By Nic Losardo (Drug Target Review) Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer...
Counteracting T-cell exhaustion in CAR-T cancer therapies 27 February 2019 | By Iqra Farooq (Drug Target Review) Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
Custom-made proteins create antibodies to fight HIV 27 February 2019 | By Drug Target Review Computational modelling has been used to design proteins that mimic the conserved protein surface of different strains of HIV for use in vaccines...
Microfluidics device to detect cancer cells in blood 26 February 2019 | By Iqra Farooq (Drug Target Review) A recently developed microfluidics device is able to detect and separate out cancer cells in blood, without the need for dilution...
Secret life of antimicrobial peptide revealed through CRISPR 26 February 2019 | By Drug Target Review Antimicrobial peptides were found to act against Gram-negative bacteria and certain fungi by working either together or by adding up their individual effects...
