Gut microbiome directs immune system to fight cancer 4 April 2019 | By Drug Target Review The advent of immune checkpoint inhibitors is a major breakthrough in cancer immunotherapy...
Creating blood vessels on demand 4 April 2019 | By Drug Target Review A new study shows that stable angiogenesis can be achieved by simply injecting a hydrogel with mechanical properties resembling that of a blood clot...
New target for chronic pain relief 3 April 2019 | By Drug Target Review Scientists observe drug target that can reduce pain when activated...
Therapeutic strategy to prevent gastrointestinal disease 2 April 2019 | By Drug Target Review New approach restores epithelial function in diarrhoea and inflammatory bowel disease models...
Computational method enhances drug target stability 1 April 2019 | By Drug Target Review Scientists have developed a new computational method for the design of thermally stable G protein-coupled receptors (GPCRs) that are of great help in creating new drugs...
New technology to produce dorsal cortical neurons using iPS 1 April 2019 | By Drug Target Review Scientists expect that it will soon be possible to treat brain diseases by restoring damaged areas in the brain by mass producing neurons using stem cells...
New mass spectrometry system for finding potential drugs 29 March 2019 | By Drug Target Review New method for computational mass spectrometry will speed up the discovery of natural products that could be used in medicines...
Heating up tumours could make CAR T therapy more effective 28 March 2019 | By Drug Target Review When a heating technique called photothermal ablation was combined with the infusion of CAR T cells, it suppressed melanoma tumour growth for up to 20 days in mice...
Scientists home in on microRNA processing for cancer therapies 27 March 2019 | By Drug Target Review Research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs...
Over 400 genes associated with schizophrenia identified 26 March 2019 | By Drug Target Review Researchers have identified new genes associated with schizophrenia and pinpointed the areas of the brain in which abnormal expression might occur...
CRISPR-Chip enables digital detection of DNA without amplification 26 March 2019 | By Drug Target Review Researchers have found multiple applications for the CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) gene editing technology since it came into use by the scientific community...
The key to greater efficacy in cancer treatment? 25 March 2019 | By Drug Target Review Mitochondria are found to be associated with the effectiveness of oncological drug therapies...
Paving the path towards precision medicine 21 March 2019 | By Drug Target Review A method to view the immune cell 'landscape' of bowel cancer tumours could pave the way towards more individualised medicine and treatment...
Epigenetic protein could be new therapeutic target in acute myeloid leukemia 19 March 2019 | By Drug Target Review The epigenetic protein, EZH2, was found to delay the development of acute myeloid leukemia (AML) but also switches sides to maintain tumour growth...
Ticagrelor reversal agent provides immediate and sustained relief 18 March 2019 | By Drug Target Review A reversal agent that sustains immediate relief from the side effects of ticagrelor stopping major bleeding, such as gastrointestinal hemorrhage...
