Novel model developed to resemble aberrant IPF lung epithelium 31 August 2021 | By Anna Begley (Drug Target Review) A new model that closely resembles aged lung epithelium in idiopathic pulmonary fibrosis has been developed, possibly leading to treatments.
NPSR1 gene discovered as a key cause of endometriosis 31 August 2021 | By Anna Begley (Drug Target Review) NPSR1 has been identified as a genetic cause of endometriosis, revealing a potential drug target that may lead to better therapies.
New precise method can visualise individual blood cells in the brain 31 August 2021 | By Anna Begley (Drug Target Review) Researchers have developed an inexpensive method for visualising blood flow in the brain that can discern the motions of individual blood cells.
Study suggests how to develop intranasal vaccines for COVID-19 and flu 30 August 2021 | By Anna Begley (Drug Target Review) New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.
Brain organoids mimic autism-related head size changes 30 August 2021 | By Anna Begley (Drug Target Review) Scientists have developed brain organoids that recapitulate the head size of autism patients to study the condition as well as possible therapies.
Detergent-like APOL3 protein shown to kill bacteria in human cells 27 August 2021 | By Anna Begley (Drug Target Review) Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.
Spike gene mutants could be used as novel COVID-19 vaccine 27 August 2021 | By Anna Begley (Drug Target Review) SARS-CoV-2 Spike gene mutants may be developed into immunogens for new vaccines against COVID-19, a study in hamsters has shown.
Cartilage growth gene TRPV4 shows promise for joint repair therapy 26 August 2021 | By Anna Begley (Drug Target Review) The discovery that the TRPV4 gene regulates cartilage growth could lead to treatments for osteoarthritis and other cartilage diseases.
Researchers identify potential drug to treat GIST tumours 26 August 2021 | By Anna Begley (Drug Target Review) A potential drug to treat a subset of gastrointestinal stroma tumours (GIST) have been found to tackle intestinal tract cancer.
Intranasal COVID-19 vaccine shown to be effective in animal models 26 August 2021 | By Anna Begley (Drug Target Review) A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.
Lung fibrosis in mice successfully reversed by scientists 25 August 2021 | By Anna Begley (Drug Target Review) A team of researchers have reversed lung fibrosis in a mouse model, highlighting a new therapeutic target for pulmonary fibrosis.
Signalling pathway identified as target against paediatric glioma 25 August 2021 | By Anna Begley (Drug Target Review) Researchers have found a vulnerability in a developmental signalling pathway, presenting a target for paediatric low-grade glioma formation.
Scientists develop novel strategy for tuberculosis vaccine 25 August 2021 | By Anna Begley (Drug Target Review) A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.
New study may improve enzyme replacement therapy for Pompe patients 24 August 2021 | By Anna Begley (Drug Target Review) Researchers have developed a new method that could make enzyme replacement therapy more efficient for Pompe disease treatment.
High-intensity focused ultrasound therapy moves closer to the clinic 24 August 2021 | By Anna Begley (Drug Target Review) Researchers are investigating how high-intensity focused ultrasound (HIFU) can work on a cellular level to treat a range of cancers.
