webinar
Biased ligands in Drug Discovery – the case of TRV027
30 June 2015 | By Cisbio Bioassays & Trevena, Inc.
TRV027 is a biased ligand; the in vitro profile and its translation into in vivo pharmacology is discussed during this webinar.
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Screening
news
Preclinical data on Neuralstem’s genetically modified HK532-IGF-1 stem cells in Alzheimer’s disease presented at ISSCR
26 June 2015 | By Victoria White
Neuralstem has presented preclinical data on genetically modified HK532-IGF-1 stem cells in Alzheimer's disease at the ISSCR Annual Meeting...
news
Researchers uncover epigenetic switches that turn stem cells into endothelial cells
26 June 2015 | By Victoria White
UIC Researchers have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells...
news
Researchers grow types of neurons affected by Parkinson’s disease
25 June 2015 | By Victoria White
Researchers have grown the types of neurons affected by Parkinson's disease, starting from neuronal stem cells in a three-dimensional cell culture system...
news
Bristol-Myers Squibb expands R&D presence in the US
25 June 2015 | By Victoria White
Bristol-Myers Squibb Company has announced important next steps in the evolution of the Company’s R&D organisation...
news
AYOXXA and Grünenthal complete research collaboration
24 June 2015 | By Victoria White
AYOXXA and Grünenthal have completed a research collaboration to validate detection limits for a biomarker based on AYOXXA’s proprietary technology platform...
video
The Science of Affimers
Find out about the science behind Affimers - including why Affimers are superior to antibodies and details about our custom Affimer process...
video
Affimers and Therapeutic Applications
Find out more about the applications of Affimers, including how Affimers can be used in the development of therapeutics...
news
Brain inflammation targeted in first Dementia Consortium drug discovery project
22 June 2015 | By Victoria White
The Dementia Consortium is funding a new project to target the immune system in the hunt for new treatments for Alzheimer's disease...
article
Targeting cancer metabolism
Cancer cells are addicted to glucose and glutamine, which enables them to generate the energy and macromolecule synthesis intermediates to support their growth...
article
The importance of adequately triaging hits from HTS campaigns
High throughput screening (HTS) continues to be employed in drug discovery as the primary source of identifying chemical starting points for drug discovery and tool compounds for chemical biology, respectively. Although small molecule drug discovery efforts have focused largely upon enzyme, receptor and ion-channel targets, there has been an increase…
video
An Introduction to Avacta Life Sciences
This video introduces Avacta Life Sciences, part of Avacta Group plc and its flagship product, Affimers - a revolutionary new, engineered alternative to antibodies...
news
SciFluor Life Sciences patented compound SF0034 highlighted in The Journal of Neuroscience
19 June 2015 | By SciFluor Life Sciences
SciFluor Life Sciences has announced that pre-clinical research demonstrating the potential effectiveness of its patented novel compound, SF0034, for treating epilepsy and preventing tinnitus was published in the peer-reviewed publication, The Journal of Neuroscience...
news
Discovery could lead to targeted melanoma therapies
18 June 2015 | By Victoria White
Melanoma patients with high levels of a protein that controls the expression of pro-growth genes are less likely to survive, according to a new study...
news
GSK invests $95m to launch Altius with goal of radically changing and improving medicines development
17 June 2015 | By Victoria White
GSK is making a substantial investment to launch the Altius Institute for Biomedical Sciences (Altius), an independent, non-profit research institute...
