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New method for early screening of colorectal cancer
A highly sensitive method that can detect even the earlier stages of colorectal cancer has been developed by researchers in Japan.
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Novel molecular pathway in cancer offers potential therapeutic targets
The gene MAFK is known to be induced by the TGF-β signalling pathway, which is involved in breast cancer development. Scientists reported that the MAFK protein, in turn, induced cancerous behaviours in cells by switching on the breast cancer-associated gene GPNMB. MAFK thus represents a link between TGF-β signalling and…
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EU funds research on biofuels and infectious diseases
Biochemist and physician Professor Ivan Dikic and microbiologist Professor Volker Müller are very honoured that their pioneering research projects have been selected for this substantial financial support.
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BenevolentAI to partner with medical research charity MRC technology
BenevolentAI, a British artificial intelligence company, has partnered with MRC Technology (MRCT), a medical research charity, to explore drug discovery initiatives in the field of small molecules and antibodies.
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Tech note: Practical tips for cellular quantification and imaging using Thermo Scientific Varioskan LUX multimode reader and Invitrogen EVOS FL Auto Cell Imaging System
This technical note offers practical tips for facilitating the use of Thermo ScientificTM VarioskanTM LUX multimode reader and InvitrogenTM EVOSTM FL Auto Cell Imaging System with the goal of achieving successful cellular quantification and imaging of mammalian cells in microplate-based assays...
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GSK: A Lifetime in Fluorescence
GSK's top investigators explain why the data quality offered by Fluorescence lifetime detection technology for drug discovery applications is superior…
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IntelliCyt launches novel assay system to accelerate cell line development
The IntelliCyt Cy-Clone™ PLUS Assay System will accelerate and improve the quality of clone ranking and selection for developing cell lines which can reduce production costs of biopharmaceuticals...
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Daiichi Sankyo to collaborate on drugs for neglected tropical diseases
Daiichi Sankyo has entered into a new joint research agreement with the Drugs for Neglected Diseases initiative (DNDi) with regard to a new research program, the Hit-to-Lead Project, with the aim of developing drug treatments for two neglected tropical diseases, leishmaniasis and Chagas disease.
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MRI use may “change the equation” for prostate cancer screening
Screening for prostate cancer is controversial. It can save lives, but it can also lead to unnecessary diagnoses, followed by surgical or radiation procedures, which themselves may lead to severe side-effects.
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Biologic treatments for inflammatory bowel disease help heal the intestine
Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.
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Brochure: Custom Assay Development
The Custom Assay Development (CAD) program at DiscoverX develops tailor-made cell lines optimised for your needs, enabling you to jump start your drug discovery programs...
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Under the microscope with Labcyte
Dr Sheraz Gul, Head of Assay Development and Screening at the Fraunhofer Institute for Molecular Biology and Applied Ecology, answers questions on assay procedures...
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Assays In-Depth Focus 2017
HTS can be carried out in a number of formats, ranging from simple biochemical (target-based) to whole animal screening assay formats. Horst Flotow, from Hit Discovery Constance, discusses the benefits and practicalities of, and recent progress in, whole animal screening. Madhu Lal-Nag, National Center for Advancing Translational Sciences, and Anton…
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Drug Target Review – Issue #1 2017
Included in this issue: Importance of building patient trust; Vaccines & Immunology; Oncology; Assays; Biomarkers; and Antibodies...
