Screening

Researchers identify key step in viral replication

14 March 2018 | By Drug Target Review

Researchers have showed how a common virus hijacks a host cell’s protein to help assemble new viruses before they are released.

Helmintex assay detects low intensity schistosomiasis infections

9 March 2018 | By Dr Zara Kassam (Drug Target Review)

Individuals who release low numbers of schistosome eggs in their faeces may now use the Helmintex method-- which uses a magnetic field to isolate eggs to detect infections...

Case Study: Characterisation of hiPSCs by Phenotypic Screening

8 March 2018 | By PerkinElmer

Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...

Application Note: Alpha Terbium SureFire Ultra Multiplex: simultaneous dual phosphoprotein target analysis

8 March 2018 | By PerkinElmer

In this application note, PerkinElmer demonstrates the measurement of two phosphoprotein targets in a single sample using the  Alpha Terbium SureFire Ultra kit combined with the AlphaLISA SureFire Ultra kit...

Kenpaullone protects from cisplatin-induced hearing loss

7 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...

Paediatric Clinical Trials

6 March 2018 | By SMi Group

When designing a Paediatric clinical trial, a paediatric investigation plan (PIP) is a development plan aimed at ensuring that the necessary data are obtained through studies in children, to support the authorisation of a medicine for children...

Bioline

Researchers find transferable antibiotic resistance gene in pathogen of developing nations

5 March 2018 | By Drug Target Review

A team of investigators has found that the mcr-1 drug resistance gene, which encodes resistance to a drug that is used as a last resort, has been found for the first time in Shigella flexneri.

Six leading pharma firms to participate at Pharmaceutical Microbiology event in San Diego

1 March 2018 | By SMi Group

SMi’s 2nd Annual Pharmaceutical Microbiology West Coast Conference will be taking place in San Diego, USA on the 7th - 8th June 2018.

Autoimmune disease research community gets boost from AMP RA/SLE study results

26 February 2018 | By Drug Target Review

Data from the Phase I study of collaborative industry partnership AMP are now available, meaning scientists can benefit from access to important research about Rheumatoid Arthritis and Systemic Lupus Erythematosus.

Single-cell RNA sequencing provides molecular atlas to study brain diseases

15 February 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have detailed a molecular atlas of the cells that form the brain's blood vessels and the life-essential blood-brain barrier providing clues to which cell types are involved in different diseases...

RT-QuIC assay adapted to test for Parkinson’s and dementia with Lewy bodies

14 February 2018 | By Dr Zara Kassam (Drug Target Review)

NIH scientists have modified an assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies...

Molecular therapy restores nerve insulation on peripheral nerves

13 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have described an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort...

Application Note: Fluorescence Polarization based assay for rapid, precise, high-throughput measurement of IgG & Fc containing derivatives

9 February 2018 | By BMG Labtech GmbH

The accurate, rapid and high-throughput measurement of IgG is essential in the development and manufacture of most therapeutic antibodies...

PSMA PET/CT clearly differentiates prostate cancer from benign tissue

9 February 2018 | By Drug Target Review

Using nuclear medicine, German researchers have found a way to accurately differentiate cancerous tissue from healthy tissue in prostate cancer patients.