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Effective approach to optimising medicinal molecules
Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...
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Recent advances in diagnostics and treatments – from small molecules to cellular therapies
14 August 2018 | By Bio-Techne
With recent advances in medicine, cellular therapies are one step closer to becoming a reality where re-programmed cells, tissues and organs can be used as therapeutic agents. This webinar discussed the journey of medical treatments from small molecule to cellular therapies...
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Drugs in development for cancer may also fight brain diseases
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
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Potential peptide drug could treat liver cancer effectively
Researchers have discovered that FFW and Sorafenib used together could reduce the growth of Sorafenib resistant hepatocellular carcinoma tumours...
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AI system designs drugs from scratch
An artificial-intelligence approach created can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates...
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The evolving role of three dimensional in-vitro cell culture techniques in drug discovery
Drug discovery is a lengthy process that proceeds through several stages. High throughput screening (HTS) utilising whole-cell based screening assays play a fundamental role as a starting point for identifying novel compounds in the drug discovery process.1,2
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Novel antibiotics can be found on common weeds
The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...
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New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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IgM antibodies protect against HIV-1 infection
A group of scientists have zeroed in on a new defence against HIV-1, the virus that causes AIDS...
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Hunger hormones offer promising avenue for addiction treatment
Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction...
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Epidemiologists highlight a link between Alzheimer’s and herpes
A new commentary by epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease...
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Researchers report success culturing Treponema pallidum, which causes syphilis
Researchers have described a new method for culturing Treponema pallidum, that until now it couldn't be cultured in a lab dish...
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Mini-ecosystems developed to test a molecules therapeutic effect
Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...
