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New mass spec technique used to determine structure of sugars
A new method has been invented that boosts the mapping of heparan sulfates and which the researchers say could be widely used for drug discovery.
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Rachael Harper (Drug Target Review)
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Human tuberculosis blood signal replicated in mice
More research into tuberculosis is now possible with the development of an optimisied mouse model that exhibits the same blood immune response to Mycobacterium tuberculosis infection as humans.
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New cancer treatment regimens could be identified with novel technology
A new technology called mass cytometry, or CyTOF, is providing new insights into a range of key proteins in blood cancer cells.
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Relationships between SLCs and cytotoxic drugs in human cells uncovered
A new systematic investigation on the role of solute carriers could lead to further insights into how the transporters affect the uptake and activity of drugs.
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Drug discovery could be improved with new collapsible basket technology
A collapsible basket technology has been developed to significantly accelerate the analysis process when scientists are developing new medicines.
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Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS)
A novel therapy, tested ex vivo, has been successful at correcting the dysfunctional body mechanism in Postural Orthostatic Tachycardia Syndrome (POTS).
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3D forces exerted by tiny cell clusters revealed through new technique
A new imaging technique, which has revealed 3D forces exerted by tiny cell clusters, could help scientists understand how tissue forms, how wounds heal or how tumours spread.
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New study helps improve the understanding of bacteria and viruses
A new study has revealed how bacterial immune systems can be harmful for their hosts and why they are not found in all bacteria.
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New therapy stops seizures in mouse model of rare childhood epilepsy
A rare form of childhood epilepsy could be improved with a therapy called antisense oligonucleotide, following the development of a new model.
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New worm model could aid in the study of rare disease
A new earthworm model has been developed for the rare disease, x-ALD, which the scientists say could lead to pharmacological targets for the neuronal alterations of the disease.
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Single cancer cells in lab-grown tumours analysed with new technology
New technology is for the first time enabling scientists to analyse the individual behaviour of millions of different cells living inside lab-grown tumours, which could lead to new personalised cancer treatments.
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Scientists can now ‘listen in’ on cancer cells with new technique
More effective drugs could be developed due to a new technique that has allowed scientists to decipher how millions of individual cells are communicating with each other on miniature tumours grown in a lab.
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Key modifier identified in genetic deletion related to autism
A key modifier has been identified by researchers in a large fruit fly genetic deletion related to neurodevelopmental disorders such as schizophrenia and autism.
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Free radicals from immune cells cause salt-sensitive hypertension
A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
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Innate protein restricts HIV replication by targeting lipid rafts
According to a new study, apolipoprotein A-I binding protein restricts HIV-1 replication by targeting lipid rafts and reducing virus-cell fusion.
