news New mass spec technique used to determine structure of sugars 25 March 2020 | By Rachael Harper (Drug Target Review) A new method has been invented that boosts the mapping of heparan sulfates and which the researchers say could be widely used for drug discovery.
news Human tuberculosis blood signal replicated in mice 24 March 2020 | By Rachael Harper (Drug Target Review) More research into tuberculosis is now possible with the development of an optimisied mouse model that exhibits the same blood immune response to Mycobacterium tuberculosis infection as humans.
news New cancer treatment regimens could be identified with novel technology 20 March 2020 | By Rachael Harper (Drug Target Review) A new technology called mass cytometry, or CyTOF, is providing new insights into a range of key proteins in blood cancer cells.
news Relationships between SLCs and cytotoxic drugs in human cells uncovered 16 March 2020 | By Rachael Harper (Drug Target Review) A new systematic investigation on the role of solute carriers could lead to further insights into how the transporters affect the uptake and activity of drugs.
news Drug discovery could be improved with new collapsible basket technology 9 March 2020 | By Rachael Harper (Drug Target Review) A collapsible basket technology has been developed to significantly accelerate the analysis process when scientists are developing new medicines.
news Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS) 9 March 2020 | By Rachael Harper (Drug Target Review) A novel therapy, tested ex vivo, has been successful at correcting the dysfunctional body mechanism in Postural Orthostatic Tachycardia Syndrome (POTS).
news 3D forces exerted by tiny cell clusters revealed through new technique 5 March 2020 | By Rachael Harper (Drug Target Review) A new imaging technique, which has revealed 3D forces exerted by tiny cell clusters, could help scientists understand how tissue forms, how wounds heal or how tumours spread.
news New study helps improve the understanding of bacteria and viruses 27 February 2020 | By Rachael Harper (Drug Target Review) A new study has revealed how bacterial immune systems can be harmful for their hosts and why they are not found in all bacteria.
news New therapy stops seizures in mouse model of rare childhood epilepsy 24 February 2020 | By Rachael Harper (Drug Target Review) A rare form of childhood epilepsy could be improved with a therapy called antisense oligonucleotide, following the development of a new model.
news New worm model could aid in the study of rare disease 21 February 2020 | By Rachael Harper (Drug Target Review) A new earthworm model has been developed for the rare disease, x-ALD, which the scientists say could lead to pharmacological targets for the neuronal alterations of the disease.
news Single cancer cells in lab-grown tumours analysed with new technology 21 February 2020 | By Rachael Harper (Drug Target Review) New technology is for the first time enabling scientists to analyse the individual behaviour of millions of different cells living inside lab-grown tumours, which could lead to new personalised cancer treatments.
news Scientists can now ‘listen in’ on cancer cells with new technique 19 February 2020 | By Rachael Harper (Drug Target Review) More effective drugs could be developed due to a new technique that has allowed scientists to decipher how millions of individual cells are communicating with each other on miniature tumours grown in a lab.
news Key modifier identified in genetic deletion related to autism 18 February 2020 | By Rachael Harper (Drug Target Review) A key modifier has been identified by researchers in a large fruit fly genetic deletion related to neurodevelopmental disorders such as schizophrenia and autism.
news Free radicals from immune cells cause salt-sensitive hypertension 12 February 2020 | By Rachael Harper (Drug Target Review) A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
news Innate protein restricts HIV replication by targeting lipid rafts 11 February 2020 | By Rachael Harper (Drug Target Review) According to a new study, apolipoprotein A-I binding protein restricts HIV-1 replication by targeting lipid rafts and reducing virus-cell fusion.
