Kamyar Hadian (Institute of Molecular Toxicology and Pharmacology)

The importance of adequately triaging hits from HTS campaigns

19 June 2015 | By Kamyar Hadian (Institute of Molecular Toxicology and Pharmacology), Kenji Schorpp (Institute of Molecular Toxicology and Pharmacology), Sheraz Gul (Fraunhofer-IME SP)

High throughput screening (HTS) continues to be employed in drug discovery as the primary source of identifying chemical starting points for drug discovery and tool compounds for chemical biology, respectively. Although small molecule drug discovery efforts have focused largely upon enzyme, receptor and ion-channel targets, there has been an increase…