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20 July 2018 | By Audrey Ncube, James Adjaye (Heinrich-Heine-University), Lisa Nguyen, Lucas-Sebastian Spitzhorn, Martina Bohndorf, Shaifur Rahman, Wasco Wruck (Heinrich-Heine-University)
Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2
17 March 2016 | By James Adjaye (Heinrich-Heine-University), Marie-Ann Kawala (Heinrich-Heine-University), Nina Graffmann (Heinrich-Heine-University), Wasco Wruck (Heinrich-Heine-University)
Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life styles and high fat diets, has an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within genes such as PNPLA3, TM6SF2, APOC3, NCAN and PPP1R3B correlate…
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