Dr Carol M Trim (Canterbury Christ Church University)

article

Transitioning novel peptide hits into lead compounds

16 December 2019 | By Dr Carol M Trim (Canterbury Christ Church University), Steven A Trim (Venomtech)

Unlike synthetic compound libraries, natural product hits must be identified and characterised, as the molecule is often unknown. Venom peptides are often inherently stable due to cysteine knots whereas other peptides may not be. Steve and Carol Trim discuss the challenges of the hit-to-lead journey with these non-standard hits.

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Dr Carol M Trim (Canterbury Christ Church University)

Transitioning novel peptide hits into lead compounds