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12 June 2015 | By Arne Hansen (University Medical Center Hamburg-Eppendorf and DZHK), Boris Greber (Max Planck Institute for Molecular Biomedicine and Chemical Genomics Centre of the Max Planck Society), Dennis Schade (Technical University of Dortmund)
Procedures for cardiac differentiation of human pluripotent stem cells (hPSCs) have greatly improved over the past few years. The facilitated derivation of hPSC-cardiomyocytes has enabled the thorough assessment of their physiology and manipulation of their properties. Moreover, patient-specific hPSCs generated through cellular reprogramming allow for cardiac disease modelling, discovery of…
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