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Arne Hansen (University Medical Center Hamburg-Eppendorf and DZHK)

 

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Human pluripotent stem cell-derived cardiomyocytes in drug discovery and development

12 June 2015 | By , ,

Procedures for cardiac differentiation of human pluripotent stem cells (hPSCs) have greatly improved over the past few years. The facilitated derivation of hPSC-cardiomyocytes has enabled the thorough assessment of their physiology and manipulation of their properties. Moreover, patient-specific hPSCs generated through cellular reprogramming allow for cardiac disease modelling, discovery of…