Baiwei Lin (Genentech Inc.)

Advanced techniques and applications of LC-MS in small molecule drug discovery

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Advanced techniques and applications of LC-MS in small molecule drug discovery

16 June 2016 | By Baiwei Lin (Genentech Inc.), Chunang Gu (Genentech Inc.), Joseph Pease (Genentech Inc.), Kate Comstock (formerly of Roche)

A key process in drug discovery is the ability to identify new drug candidates by screening chemical libraries of small molecules, natural products or extracts against a biological target and selecting lead compounds with desirable therapeutic effects. Medicinal chemistry has the challenging role of not only ensuring that the chemical…

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Baiwei Lin (Genentech Inc.)

Advanced techniques and applications of LC-MS in small molecule drug discovery