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ulcerative colitis

Targeting TNF to treat Dupuytren’s disease, frozen shoulder and POCD

20 April 2021 | By Dr James Woody (180 Life Sciences)

Dr James Woody discusses off-patent indications for anti-TNF to address unmet patient needs in pain, inflammation and beyond.

news

Inflammatory bowel disease drugs could combat COVID-19, study suggests

6 November 2020 | By Victoria Rees (Drug Target Review)

Anti-inflammatory therapies for inflammatory bowel disease could aid recovery from COVID-19 as they target an enzyme involved in both diseases.

article

Could novel sex-linked targets provide an autoimmunity therapy?

20 January 2020 | By Hannah Balfour (Drug Target Review)

Recent research into why autoimmune disorders affect women four times more frequently than men has revealed several novel therapeutic targets that may lead to the development of future treatments.

news

ImmunoPET imaging noninvasively pinpoints colitis inflammation

7 June 2018 | By Drug Target Review

A novel PET imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease...

news

Precision editing of gut bacteria used to treat colitis

8 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis...

news

Researchers produce the first draft cell atlas of the small intestine

8 November 2017 | By Dr Zara Kassam (Drug Target Review)

By surveying gene expression, researchers have created a reference atlas for understanding the biology of inflammatory bowel disease and food allergies, among other conditions...

news

Paediatric ulcerative colitis drug gets orphan designation

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

The U.S. Food and Drug Administration has granted an orphan-drug designation to cobitolimod for the treatment of ulcerative colitis in pediatric patients...

news

Biologic treatments for inflammatory bowel disease help heal the intestine

27 March 2017 | By Niamh Marriott (Drug Target Review)

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

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ulcerative colitis